I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed
by the presence of both subjective and objective evidence of chronic sinonasal …

There are a variety of medical conditions associated with chronic sinonasal inflammation,
including chronic rhinosinusitis (CRS) and cystic fibrosis. In particular, CRS can be divided …

Chronic rhinosinusitis can be differentiated into several phenotypes based on clinical
criteria; however, these phenotypes do not teach us much about the underlying inflammatory …

abstract Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local
inflammation of the upper airways and sinuses which persists for at least 12 weeks. CRS …

Rationale: The mechanisms that underlie the pathogenesis of chronic rhinosinusitis without
nasal polyps (CRSsNP), chronic rhinosinusitis with nasal polyps (CRSwNP), and aspirin …

Background Chronic rhinosinusitis (CRS) without nasal polyps (CRSsNP) is a common
disease that is characterized by multiple inflammatory endotypes. However, the molecular …

Chronic rhinosinusitis with nasal polyps (CRS w NP) is a complex inflammatory condition
that affects a large proportion of the population world‐wide and is associated with high cost …

Basophils are the rarest granulocytes and have long been overlooked in immunological
research due to their rarity and similarities with tissue-resident mast cells. In the last two …