Structural insights into the activation mechanism of antimicrobial GBP1
The dynamin-related human guanylate-binding protein 1 (GBP1) mediates host defenses
against microbial pathogens. Upon GTP binding and hydrolysis, auto-inhibited GBP1 …
against microbial pathogens. Upon GTP binding and hydrolysis, auto-inhibited GBP1 …
Structural requirements for membrane binding of human guanylate‐binding protein 1
Human guanylate‐binding protein 1 (hGBP1) is a key player in innate immunity and fights
diverse intracellular microbial pathogens. Its antimicrobial functions depend on hGBP1's …
diverse intracellular microbial pathogens. Its antimicrobial functions depend on hGBP1's …
Elucidating the activation mechanism for GBP1 oligomerization
The dynamin-related human guanylate-binding protein 1 (GBP1) mediates host defense
against microbial pathogens. Upon GTP binding and hydrolysis, auto-inhibited GBP1 …
against microbial pathogens. Upon GTP binding and hydrolysis, auto-inhibited GBP1 …
Recruitment of Guanylate-Binding Proteins to Francisella novicida in human macrophages
S Valeva - 2022 - theses.hal.science
Francisella novicida is a professional cytosol dwelling pathogen, internalized by host cells
(macrophages, neutrophils) through phagocytosis. F. novicida escapes from the phagosome …
(macrophages, neutrophils) through phagocytosis. F. novicida escapes from the phagosome …