Tumor cell and immune cell profiles in primary human glioblastoma: Impact on patient outcome
M González‐Tablas Pimenta, Á Otero… - Brain …, 2021 - Wiley Online Library
The distribution and role of tumor‐infiltrating leucocytes in glioblastoma (GBM) remain
largely unknown. Here, we investigated the cellular composition of 55 primary (adult) GBM …
largely unknown. Here, we investigated the cellular composition of 55 primary (adult) GBM …
Gene expression-based biomarkers designating glioblastomas resistant to multiple treatment strategies
Despite advances in molecular characterization of glioblastoma multiforme (GBM), only a
handful of predictive biomarkers exist with limited clinical relevance. We aimed to identify …
handful of predictive biomarkers exist with limited clinical relevance. We aimed to identify …
[HTML][HTML] Heterogeneous EGFR, CDK4, MDM4, and PDGFRA Gene Expression Profiles in Primary GBM: No Association with Patient Survival
M González-Tablas, D Arandia, M Jara-Acevedo… - Cancers, 2020 - mdpi.com
Background: The prognostic impact of the expression profile of genes recurrently amplified
in glioblastoma multiforme (GBM) remains controversial. Methods: We investigated the RNA …
in glioblastoma multiforme (GBM) remains controversial. Methods: We investigated the RNA …
[HTML][HTML] Development of a risk-stratification scoring system for predicting lymphovascular invasion in breast cancer
M Ni-jia-ti, D Ai-hai-ti, A Huo-jia, P Wu-mai-er… - BMC cancer, 2020 - Springer
Background Lymphovascular invasion (LVI) is a vital risk factor for prognosis across
cancers. We aimed to develop a scoring system for stratifying LVI risk in patients with breast …
cancers. We aimed to develop a scoring system for stratifying LVI risk in patients with breast …
[HTML][HTML] Targeting chromosome 12q amplification in relapsed glioblastoma: the use of computational biological modeling to identify effective therapy—a case report
MP Castro, N Khanlou, A Fallah… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Relapsed glioblastoma (GBM) is often an imminently fatal condition with limited
therapeutic options. Computation biological modeling, ie, biosimulation, of comprehensive …
therapeutic options. Computation biological modeling, ie, biosimulation, of comprehensive …
Análisis de las alteraciones genéticas y del microambiente inmune tumoral en pacientes con gliobastoma: impacto en el curso clínico del tumor
M González-Tablas Pimenta - 2022 - gredos.usal.es
En el contexto en el que muchos de los genes alterados en el GB son diana de distintas
vías de señalización celular estratégicas (p. ej. vías cuya alteración puede estar asociada …
vías de señalización celular estratégicas (p. ej. vías cuya alteración puede estar asociada …
[PDF][PDF] EGFR Amplification in a Patient with Glioblastoma: A Case Report and Review of the Literature.
R Hurtado, E Peng, J Yee, C Tran… - Journal of the …, 2022 - researchgate.net
Glioblastoma Multiforme (GBM) is the most malignant and frequently occurring primary brain
tumor out of the different types of primary astrocytomas. It presents with an extremely poor …
tumor out of the different types of primary astrocytomas. It presents with an extremely poor …
[引用][C] PHASE I CLINICAL TRIAL ON INTRA-TUMORAL IPILIMUMAB PLUS INTRAVENOUS NIVOLUMAB FOLLOWING THE RESECTION OF RECURRENT …
S Peeters - 2019