Abstract (Poly) phenols (PPs) constitute a large family of phytochemicals with high chemical
diversity that are known to be active principles of plant-derived nutraceuticals and herbal …

Cardiovascular diseases (CVDs) cause the largest mortality worldwide, and much attention
has been focused to unravel the mechanisms and optimize the treatment regimens …

Diabetes mellitus (DM) refers to a group of metabolic disorders that are characterized by
hyperglycemia. Oral subcutaneously administered antidiabetic drugs such as insulin …

In recent years, the interaction between the bioactive ingredients of traditional Chinese
medicine (TCM) and gut microbiota has been a focus of many studies. When TCM enters the …

Ethnopharmacological relevance Herb–drug interactions are of great concern in health
practices. Curcumin is a natural polyphenol extracted from turmeric, a spice widely used all …

Purpose Suppression of inflammation and oxidative stress is an attractive strategy to against
diabetic cardiomyopathy (DCM). Kaempferol (KPF) exerts both anti-inflammatory and …

Diabetic cardiomyopathy is one of the main causes of heart failure and death in patients with
diabetes mellitus. Reactive oxygen species produced excessively in diabetes mellitus cause …

The metabolic syndrome (MS) is a multifactorial syndrome associated with a significant
economic burden and healthcare costs. MS management often requires multiple treatments …

Metformin is one of the most commonly prescribed antidiabetic drugs. A recent clinical study
has highlighted the protective role of metformin against cardiac complications in type I …

It has been extensively verified that inflammation and oxidative stress play important roles in
the pathogenesis of cardiovascular diseases (CVDs). Curcuminoids, from the plant Curcuma …