Among various types of ion species, carbon ions are considered to have the most balanced,
optimal properties in terms of possessing physically and biologically effective dose …

CONTEXT: Prostate cancer (PCa) patients have many options within the realms of surgery
or radiation therapy (RT). Technical advancements in RT planning and delivery have …

Purpose Conventional radiotherapy (C-RT) treatment schedules for patients with prostate
cancer typically require 40 to 45 treatments that take place from> 8 to 9 weeks. Preclinical …

Purpose The effectiveness of stereotactic body radiotherapy (SBRT) for localized prostate
cancer is tested. Methods and materials A total of 1100 patients with clinically localized …

Background Several studies have reported a low α to β ratio for prostate cancer, suggesting
that hypofractionation could enhance the biological tumour dose without increasing …

PURPOSE: Hypofractionated radiotherapy has an intrinsically different normal tissue and
tumor radiobiology. The results of a prospective trial of stereotactic body radiotherapy …

Background Prostate cancer might have high radiation-fraction sensitivity, implying a
therapeutic advantage of hypofractionated treatment. We present a pre-planned preliminary …

Purpose. To determine the dose response parameters and the fractionation sensitivity of
prostate tumours from clinical results of patients treated with external beam radiotherapy …

Background In 2007, we began the randomised phase 3 multicentre HYPRO trial to
investigate the effect of hypofractionated radiotherapy compared with conventionally …

A great deal of quantitative information regarding the dose–volume relationships of pelvic
organs at risk has been collected and analysed over the last 10 years. The need to improve …