Biological activities and emerging roles of lignin and lignin-based products─ A review
Bioactive substances, displaying excellent biocompatibility, chemical stability, and
processability, could be extensively applied in biomedicine and tissue engineering. In recent …
processability, could be extensively applied in biomedicine and tissue engineering. In recent …
Lignins and their derivatives with beneficial effects on human health
MP Vinardell, M Mitjans - International journal of molecular sciences, 2017 - mdpi.com
A review of the pharmacological applications of lignins provides evidence of their protective
role against the development of different diseases. In many cases, the effects of lignins could …
role against the development of different diseases. In many cases, the effects of lignins could …
The structure of glycosaminoglycans and their interactions with proteins
NS Gandhi, RL Mancera - Chemical biology & drug design, 2008 - Wiley Online Library
Glycosaminoglycans (GAGs) are important complex carbohydrates that participate in many
biological processes through the regulation of their various protein partners. Biochemical …
biological processes through the regulation of their various protein partners. Biochemical …
Chemical sulfation of small molecules—Advances and challenges
RA Al-Horani, UR Desai - Tetrahedron, 2010 - Elsevier
In a 1876 report Eugen Baumann described the isolation of a crystalline 'phenol-
forming'substance from horse urine and showed that the substance was related to m-and p …
forming'substance from horse urine and showed that the substance was related to m-and p …
Chemistry and occurrence of hydroxycinnamate oligomers
M Bunzel - Phytochemistry Reviews, 2010 - Springer
Hydroxycinnamates such as ferulic acid, sinapic acid and p-coumaric acid ester-linked to
plant cell wall polymers may act as cross-links between polysaccharides to each other, but …
plant cell wall polymers may act as cross-links between polysaccharides to each other, but …
Recent advances in the discovery and development of factor XI/XIa inhibitors
RA Al‐Horani, DK Afosah - Medicinal research reviews, 2018 - Wiley Online Library
Abstract Factor XIa (FXIa) is a serine protease homodimer that belongs to the intrinsic
coagulation pathway. FXIa primarily catalyzes factor IX activation to factor IXa, which …
coagulation pathway. FXIa primarily catalyzes factor IX activation to factor IXa, which …
Emerging sulfated flavonoids and other polyphenols as drugs: Nature as an inspiration
M Correia‐da‐Silva, E Sousa… - Medicinal research …, 2014 - Wiley Online Library
Nature uses sulfation of endogenous and exogenous molecules mainly to avoid potential
toxicity. The growing importance of natural sulfated molecules, as modulators of a number of …
toxicity. The growing importance of natural sulfated molecules, as modulators of a number of …
Recent advances on plasmin inhibitors for the treatment of fibrinolysis‐related disorders
RA Al‐Horani, UR Desai - Medicinal research reviews, 2014 - Wiley Online Library
Growing evidence suggests that plasmin is involved in a number of physiological processes
in addition to its key role in fibrin cleavage. Plasmin inhibition is critical in preventing …
in addition to its key role in fibrin cleavage. Plasmin inhibition is critical in preventing …
Nature of hydroxycinnamate-protein interactions
HM Rawel, S Rohn - Phytochemistry Reviews, 2010 - Springer
In the context of this review the type and nature of possible interactions between
hydroxycinnamates and proteins are discussed. These interactions can be classified in two …
hydroxycinnamates and proteins are discussed. These interactions can be classified in two …
[HTML][HTML] A systems pharmacology approach to investigate the mechanism of Oryeong-san formula for the treatment of hypertension
SK Kim, S Lee, MK Lee, S Lee - Journal of ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance Oryeong-san (ORS) is a traditional formula that has long
been used for the treatment of dysfunctions of body fluids and electrolyte homeostasis in …
been used for the treatment of dysfunctions of body fluids and electrolyte homeostasis in …