Pyroptosis is an inflammatory form of cell death triggered by certain inflammasomes, leading
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …

Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …

Triple-negative breast cancer (TNBC) is associated with an increased risk of early
recurrence and distant metastasis, as well as the development of therapeutic resistance and …

Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …

Triple-negative breast cancer (TNBC) is not as prevalent as hormone receptor or HER2-
positive breast cancers and all receptor tests come back negative. More importantly, the …

Chemo-resistance and metastasis of triple negative breast cancer (TNBC) contributed the
most of treatment failure in the clinic. MicroRNAs (miRNAs) have been proved to be involved …

Triple negative breast cancer (TNBC) is difficult to treat effectively, due to its aggressiveness,
drug resistance, and lack of the receptors required for hormonal therapy, particularly at the …

Background Triple-negative breast cancer (TNBC) is often aggressive and associated with a
poor prognosis. Due to the lack of available targeted therapies and to problems of resistance …

Background Metastatic triple-negative breast cancer (mTNBC) has a poor prognosis and
aggressive clinical course. tnAcity evaluated the efficacy and safety of first-line nab …

Triple-negative breast cancer (TNBC) is the most complex and aggressive type of breast
cancer encountered world widely in women. Absence of hormonal receptors on breast …