Thiol switches in mitochondria: operation and physiological relevance

J Riemer, M Schwarzländer, M Conrad… - Biological …, 2015 - degruyter.com
Mitochondria are a major source of reactive oxygen species (ROS) in the cell, particularly of
superoxide and hydrogen peroxide. A number of dedicated enzymes regulate the …

Functional characterization of a vanillin dehydrogenase in Corynebacterium glutamicum

W Ding, M Si, W Zhang, Y Zhang, C Chen, L Zhang… - Scientific reports, 2015 - nature.com
Vanillin dehydrogenase (VDH) is a crucial enzyme involved in the degradation of lignin-
derived aromatic compounds. Herein, the VDH from Corynebacterium glutamicum was …

Structure-based mutational studies of substrate inhibition of betaine aldehyde dehydrogenase BetB from Staphylococcus aureus

C Chen, JC Joo, G Brown, E Stolnikova… - Applied and …, 2014 - Am Soc Microbiol
Inhibition of enzyme activity by high concentrations of substrate and/or cofactor is a general
phenomenon demonstrated in many enzymes, including aldehyde dehydrogenases. Here …

Structural characterization of Linum usitatissimum hydroxynitrile lyase: A new cyanohydrin decomposition mechanism involving a cyano-zinc complex

D Zheng, M Nakabayashi, Y Asano - Journal of Biological Chemistry, 2022 - ASBMB
Hydroxynitrile lyase from Linum usitatissimum (LuHNL) is an enzyme involved in the
catabolism of cyanogenic glycosides to release hydrogen cyanide upon tissue damage. This …

Aldehyde dehydrogenase enzyme ALDH3H1 from Arabidopsis thaliana: Identification of amino acid residues critical for cofactor specificity

N Stiti, K Podgorska, D Bartels - … et Biophysica Acta (BBA)-Proteins and …, 2014 - Elsevier
The cofactor-binding site of the NAD+-dependent Arabidopsis thaliana aldehyde
dehydrogenase ALDH3H1 was analyzed to understand structural features determining …

Inhibition of homoserine dehydrogenase by formation of a cysteine-NAD covalent complex

K Ogata, Y Yajima, S Nakamura, R Kaneko, M Goto… - Scientific reports, 2018 - nature.com
Abstract Homoserine dehydrogenase (EC 1.1. 1.3, HSD) is an important regulatory enzyme
in the aspartate pathway, which mediates synthesis of methionine, threonine and isoleucine …

[PDF][PDF] Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus

AS Halavaty, RL Rich, C Chen, JC Joo… - … Section D: Biological …, 2015 - journals.iucr.org
When exposed to high osmolarity, methicillin-resistant Staphylococcus aureus (MRSA)
restores its growth and establishes a new steady state by accumulating the osmoprotectant …

S-Nitrosation impairs activity of stress-inducible aldehyde dehydrogenases from Arabidopsis thaliana

N Stiti, KA Podgórska, D Bartels - Plant Science, 2020 - Elsevier
Nitric oxide (NO radical dot) is an intracellular messenger that mediates stress responses.
Several plant aldehyde dehydrogenase (ALDH) genes are expressed during abiotic stress …

The uncharacterized Pseudomonas aeruginosa PA4189 is a novel and efficient aminoacetaldehyde dehydrogenase

A Fernández-Silva, AL Juárez-Vázquez… - Biochemical …, 2023 - portlandpress.com
Neither the Pseudomonas aeruginosa aldehyde dehydrogenase encoded by the PA4189
gene nor its ortholog proteins have been biochemically or structurally characterized and …

Structural basis for a cofactor-dependent oxidation protection and catalysis of cyanobacterial succinic semialdehyde dehydrogenase

J Park, S Rhee - Journal of Biological Chemistry, 2013 - ASBMB
Succinic semialdehyde dehydrogenase (SSADH) from cyanobacterium Synechococcus
differs from other SSADHs in the γ-aminobutyrate shunt. Synechococcus SSADH …