Overview of the 2022 WHO classification of paragangliomas and pheochromocytomas
This review summarizes the classification of tumors of the adrenal medulla and extra-
adrenal paraganglia as outlined in the 5th series of the WHO Classification of Endocrine and …
adrenal paraganglia as outlined in the 5th series of the WHO Classification of Endocrine and …
Recent advances in the developmental origin of neuroblastoma: an overview
M Ponzoni, T Bachetti, MV Corrias, C Brignole… - Journal of Experimental …, 2022 - Springer
Neuroblastoma (NB) is a pediatric tumor that originates from neural crest-derived cells
undergoing a defective differentiation due to genomic and epigenetic impairments …
undergoing a defective differentiation due to genomic and epigenetic impairments …
Spatiotemporal structure of cell fate decisions in murine neural crest
Neural crest cells are embryonic progenitors that generate numerous cell types in
vertebrates. With single-cell analysis, we show that mouse trunk neural crest cells become …
vertebrates. With single-cell analysis, we show that mouse trunk neural crest cells become …
Single-cell characterization of malignant phenotypes and developmental trajectories of adrenal neuroblastoma
R Dong, R Yang, Y Zhan, HD Lai, CJ Ye, XY Yao… - Cancer Cell, 2020 - cell.com
Neuroblastoma (NB), which is a subtype of neural-crest-derived malignancy, is the most
common extracranial solid tumor occurring in childhood. Despite extensive research, the …
common extracranial solid tumor occurring in childhood. Despite extensive research, the …
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Abstract Characterization of the progression of cellular states during human embryogenesis
can provide insights into the origin of pediatric diseases. We examined the transcriptional …
can provide insights into the origin of pediatric diseases. We examined the transcriptional …
Schwann cell precursors represent a neural crest‐like state with biased multipotency
ME Kastriti, L Faure, D Von Ahsen… - The EMBO …, 2022 - embopress.org
Schwann cell precursors (SCPs) are nerve‐associated progenitors that can generate
myelinating and non‐myelinating Schwann cells but also are multipotent like the neural …
myelinating and non‐myelinating Schwann cells but also are multipotent like the neural …
Riding the crest to get a head: neural crest evolution in vertebrates
ML Martik, ME Bronner - Nature Reviews Neuroscience, 2021 - nature.com
In their seminal 1983 paper, Gans and Northcutt proposed that evolution of the vertebrate
'new head'was made possible by the advent of the neural crest and cranial placodes. The …
'new head'was made possible by the advent of the neural crest and cranial placodes. The …
Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment
Pheochromocytomas (PC) and paragangliomas (PG) are rare neuroendocrine tumors
associated with autonomic nerves. Here we use single-nuclei RNA-seq and bulk-tissue …
associated with autonomic nerves. Here we use single-nuclei RNA-seq and bulk-tissue …
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Neuroblastoma is a childhood cancer that resembles developmental stages of the neural
crest. It is not established what developmental processes neuroblastoma cancer cells …
crest. It is not established what developmental processes neuroblastoma cancer cells …
Cracking the enigma of adenomyosis: an update on its pathogenesis and pathophysiology
SW Guo - Reproduction, 2022 - rep.bioscientifica.com
In brief Traditionally viewed as enigmatic and elusive, adenomyosis is a fairly common
gynecological disease but is under-recognized and under-researched. This review …
gynecological disease but is under-recognized and under-researched. This review …