Methods and systems for converting precursor cells into gastric tissues through directed differentiation

JM Wells, KW Mccracken - US Patent 11,053,477, 2021 - Google Patents
US11053477B2 - Methods and systems for converting precursor cells into gastric tissues
through directed differentiation - Google Patents US11053477B2 - Methods and systems for …

Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same

J Wells, K McCracken - US Patent 11,066,650, 2021 - Google Patents
The instant disclosure relates to methods for converting mammalian definitive endoderm
(DE) cells into specific tissue (s) or organ (s) through directed differentiation. In particular, the …

Method of making in vivo human small intestine organoids from pluripotent stem cells

JM Wells, CL Watson, JO Munera, MM Mahe… - US Patent …, 2023 - Google Patents
2017-05-17 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …

Method of determining a distribution of stem cells in a cell image, electronic device, and storage medium

WJ Lee, CP Kuo, CT Lu - US Patent 12,106,474, 2024 - Google Patents
A method of determining a distribution of stem cells in a cell image, an electronic device and
a storage medium are disclosed. The method acquires a cell image and segments the cell …

Colonic organoids and methods of making and using same

JM Wells, JO Munera - US Patent 11,767,515, 2023 - Google Patents
Disclosed herein are methods for the in vitro differentiation of a precursor cell into definitive
endoderm, which may further be differentiated into a human colonic organoid (HCO), via …