Functions of antibodies
DN Forthal - Microbiology spectrum, 2014 - Am Soc Microbiol
Antibodies can impact pathogens in the presence or in the absence of effector cells or
effector molecules such as complement, and experiments can often sort out with precision …
effector molecules such as complement, and experiments can often sort out with precision …
[HTML][HTML] Glycosaminoglycan-protein interactions and their roles in human disease
D Shi, A Sheng, L Chi - Frontiers in molecular biosciences, 2021 - frontiersin.org
Glycosaminoglycans (GAGs) are a family of linear and negatively charged polysaccharides
that exist ubiquitously on the human cell surface as well as in the extracellular matrix. GAGs …
that exist ubiquitously on the human cell surface as well as in the extracellular matrix. GAGs …
Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
Variant surface antigens of Plasmodium falciparum and their roles in severe malaria
Proliferation and differentiation inside erythrocytes are important steps in the life cycle of
Plasmodium spp. To achieve these, the parasites export polypeptides to the surface of …
Plasmodium spp. To achieve these, the parasites export polypeptides to the surface of …
[HTML][HTML] Targeting human cancer by a glycosaminoglycan binding malaria protein
A Salanti, TM Clausen, MØ Agerbæk, N Al Nakouzi… - Cancer cell, 2015 - cell.com
Plasmodium falciparum engineer infected erythrocytes to present the malarial protein,
VAR2CSA, which binds a distinct type chondroitin sulfate (CS) exclusively expressed in the …
VAR2CSA, which binds a distinct type chondroitin sulfate (CS) exclusively expressed in the …
Malaria's deadly grip: cytoadhesion of Plasmodium falciparum‐infected erythrocytes
Cytoadhesion of P lasmodium falciparum‐infected erythrocytes to host microvasculature is a
key virulence determinant. Parasite binding is mediated by a large family of clonally variant …
key virulence determinant. Parasite binding is mediated by a large family of clonally variant …
New insights into malaria pathogenesis
Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …
[HTML][HTML] The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner
MØ Agerbæk, SR Bang-Christensen, MH Yang… - Nature …, 2018 - nature.com
Isolation of metastatic circulating tumor cells (CTCs) from cancer patients is of high value for
disease monitoring and molecular characterization. Despite the development of many new …
disease monitoring and molecular characterization. Despite the development of many new …
Malaria biomimetic for tumor targeted drug delivery
Malaria infected erythrocytes utilize the parasite protein VAR2CSA to bind to a unique
presentation of chondroitin sulfate (CS) for their placenta specific tropism. Interestingly …
presentation of chondroitin sulfate (CS) for their placenta specific tropism. Interestingly …
PfEMP1–a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis
L Hviid, ATR Jensen - Advances in parasitology, 2015 - Elsevier
Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …