Application of amorphous solid dispersions (ASDs) is considered one of the most promising
approaches to increase the dissolution rate and extent of bioavailability of poorly water …

Microcrystalline cellulose (MCC) is one of the most popular cellulose derivatives in the
pharmaceutical industry. Thanks to its outstanding tabletability, MCC is generally included in …

It is necessary to have excipients with excellent functional properties to compensate for the
poor mechanical properties and low aqueous solubility of the emerging active ingredients …

With the advancement of tablet manufacturing process, the demand of excipients with
improved functionalities, mainly in terms of flow and compression properties, has increased …

The demands on the functionality of excipients are increasing day by day because of the
emergence of high-speed tableting machines and the use of direct compression methods for …

Co-processed excipients may enhance functionality and reduce drawbacks of traditional
excipients for the manufacture of tablets on a commercial scale. The following study aimed …

Tableting by direct compression (DC) is one of the simplest and most cost-effective drug
manufacturing approaches. However, most active pharmaceutical ingredients (APIs) and …

Ebastine is a long‐acting, nonsedating, second‐generation antihistaminic drug that prevents
histamine action, mainly in immediate hypersensitivity. This project was aimed to formulate …

In this study, a co-processed excipient (Cop AA-MCC) was prepared from alginic acid (AA)
and microcrystalline cellulose (MCC101) using a laboratory scale high-shear granulator …

There is no single-component excipient fulfills all the requisite performance to allow an
active pharmaceutical ingredient to be formulated into a specific dosage form. Co-processed …