The crosstalk between the matrix metalloprotease system and the chemokine network in acute myeloid leukemia

KJ Hatfield, H Reikvam… - Current medicinal …, 2010 - ingentaconnect.com
Matrix metalloproteinases (MMPs) comprise a large family of zinc-dependent
endopeptidases, which are best known for their ability to degrade essentially all components …

[HTML][HTML] Vascular disruption and the role of angiogenic proteins after spinal cord injury

MTL Ng, AT Stammers, BK Kwon - Translational stroke research, 2011 - Springer
Spinal cord injuries (SCI) can result in devastating paralysis, for which there is currently no
robustly efficacious neuroprotective/neuroregenerative treatment. When the spinal cord is …

Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia

SM Kornblau, D McCue, N Singh… - Blood, The Journal …, 2010 - ashpublications.org
The role of circulating cytokines and chemokines (C&Ckine) in activating signal transduction
in leukemic cells is incompletely defined. We hypothesized that comprehensive profiling of …

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal …

C Langer, MD Radmacher, AS Ruppert… - Blood, The Journal …, 2008 - ashpublications.org
BAALC expression is considered an independent prognostic factor in cytogenetically normal
acute myeloid leukemia (CN-AML), but has yet to be investigated together with multiple …

Fabrication of a three-dimensional bone marrow niche-like acute myeloid Leukemia disease model by an automated and controlled process using a robotic …

DM Alhattab, I Isaioglou, S Alshehri, ZN Khan… - Biomaterials …, 2023 - spj.science.org
Background Acute myeloid leukemia (AML) is a hematological malignancy that remains a
therapeutic challenge due to the high incidence of disease relapse. To better understand …

BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically …

S Schwind, G Marcucci, K Maharry… - Blood, The Journal …, 2010 - ashpublications.org
BAALC and ERG expression levels are prognostic markers in younger (< 60 years)
cytogenetically normal acute myeloid leukemia (CN-AML) adults; their prognostic impact in …

Cytokine regulation of microenvironmental cells in myeloproliferative neoplasms

G Hoermann, G Greiner, P Valent - Mediators of inflammation, 2015 - Wiley Online Library
The term myeloproliferative neoplasms (MPN) refers to a heterogeneous group of diseases
including not only polycythemia vera (PV), essential thrombocythemia (ET), and primary …

The Potential of Angiogenin as a Serum Biomarker for Diseases: Systematic Review and Meta‐Analysis

D Yu, Y Cai, W Zhou, J Sheng, Z Xu - Disease markers, 2018 - Wiley Online Library
Background. Angiogenin (ANG) is a multifunctional angiogenic protein that participates in
both normal development and diseases. Abnormal serum ANG levels are commonly …

[HTML][HTML] Neutrophil gelatinase-associated lipocalin (NGAL), pro-matrix metalloproteinase-9 (pro-MMP-9) and their complex pro-MMP-9/NGAL in leukaemias

S Bouchet, B Bauvois - Cancers, 2014 - mdpi.com
Matrix metalloproteinase (MMP)-9 and neutrophil gelatinase-associated lipocalin (NGAL)
have gained attention as cancer biomarkers. The inactive zymogen form of MMP-9 (pro …

Identification of a subset of patients with acute myeloid leukemia characterized by long-term in vitro proliferation and altered cell cycle regulation of the leukemic cells

KJ Hatfield, H Reikvam, Ø Bruserud - Expert opinion on therapeutic …, 2014 - Taylor & Francis
Objective: The malignant cell population of acute myeloid leukemia (AML) includes a small
population of stem/progenitor cells with long-term in vitro proliferation. We wanted to …