[HTML][HTML] Advances and challenges in stem cell culture
C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …
medicine as well as pharmaceutical and biotechnological applications. They have the …
[HTML][HTML] Microfluidic platforms for cell cultures and investigations
This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …
of both adherent and non-adherent cells, including a multitude of applications. A comparison …
Engineering prostate cancer in vitro: what does it take?
A key challenge in the clinical management and cause of treatment failure of prostate cancer
(PCa) is its molecular, cellular and clinical heterogeneity. Modelling systems that fully …
(PCa) is its molecular, cellular and clinical heterogeneity. Modelling systems that fully …
Controlling stem cell fate with material design
RA Marklein, JA Burdick - Advanced materials, 2010 - Wiley Online Library
Advances in our understanding of stem cell interactions with their environment are leading
to the development of new materials‐based approaches to control stem cell behavior toward …
to the development of new materials‐based approaches to control stem cell behavior toward …
An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells
H Tsutsui, B Valamehr, A Hindoyan, R Qiao… - Nature …, 2011 - nature.com
A major challenge in stem cell-mediated regenerative medicine is the development of
defined culture systems for the maintenance of clinical-grade human embryonic stem (hES) …
defined culture systems for the maintenance of clinical-grade human embryonic stem (hES) …
Cell mechanics in embryoid bodies
K Zeevaert, MH Elsafi Mabrouk, W Wagner, R Goetzke - Cells, 2020 - mdpi.com
Embryoid bodies (EBs) resemble self-organizing aggregates of pluripotent stem cells that
recapitulate some aspects of early embryogenesis. Within few days, the cells undergo a …
recapitulate some aspects of early embryogenesis. Within few days, the cells undergo a …
Mass transfer limitations in embryoid bodies during human embryonic stem cell differentiation
Due to their ability to differentiate into cell types from all the three germ layers and their
potential unlimited capacity for expansion, embryonic stem cells have tremendous potential …
potential unlimited capacity for expansion, embryonic stem cells have tremendous potential …
In situ generation of human brain organoids on a micropillar array
Brain organoids derived from human induced pluripotent stem cells can recapitulate the
early stages of brain development, representing a powerful in vitro system for modeling …
early stages of brain development, representing a powerful in vitro system for modeling …
Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation
Biomaterials are increasingly being used to engineer the biochemical and biophysical
properties of the extracellular stem cell microenvironment in order to tailor niche …
properties of the extracellular stem cell microenvironment in order to tailor niche …