An overview of the co-transcription factor NACC1: beyond its pro-tumor effects
Q Xie, C Tong, X Xiong - Life Sciences, 2024 - Elsevier
Nucleus accumbens-associated protein 1 (NACC1) is a member of the broad complex,
tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) protein families, mainly exerting its …
tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) protein families, mainly exerting its …
NAC1 transcriptional activation of LDHA induces hepatitis B virus immune evasion leading to cirrhosis and hepatocellular carcinoma development
W Chen, L Guo, H Xu, Y Dai, J Yao, L Wang - Oncogenesis, 2024 - nature.com
Our study aimed to elucidate the molecular mechanisms underlying NAC1 (nucleus
accumbens associated 1) transcriptional regulation of LDHA and its role in HBV immune …
accumbens associated 1) transcriptional regulation of LDHA and its role in HBV immune …
[HTML][HTML] Nucleus Accumbens Associated Protein 1 in Cancers—The Real Value
M Janiczek-Polewska, T Kolenda, P Poter… - International Journal of …, 2024 - mdpi.com
Malignant tumors are a leading cause of death worldwide, second only to cardiovascular
disease. They occur in every population and have a high risk of mortality. The …
disease. They occur in every population and have a high risk of mortality. The …
[HTML][HTML] eEF-2K Deficiency Boosts the Virus-Specific Effector CD8+ T Cell Responses During Viral Infection
L Wang, BS Song, R Poojary, X Xiong, X Ren, JM Yang… - Viruses, 2024 - mdpi.com
In this study, we revealed a critical role of eukaryotic elongation factor-2 kinase (eEF-2K), a
negative regulator of protein synthesis, in regulating T cells during vaccinia virus (VACV) …
negative regulator of protein synthesis, in regulating T cells during vaccinia virus (VACV) …
Case report: A novel de novo variant of NACC1 caused epileptic encephalopathy and intellectual disability
J Wu, J Gan, Y Hua, Y Li, D Qie - Frontiers in Psychiatry, 2024 - frontiersin.org
Background Genetic disorders could also contribute to intellectual disability. Using whole
exome sequencing (WES), several variants have been identified as autosomal-dominant …
exome sequencing (WES), several variants have been identified as autosomal-dominant …
Role of T Cells in Microbial Pathogenesis
The immune system functions as a sophisticated defense mechanism, shielding the body
from harmful pathogenic invaders. Various types of immune cells collaborate in response to …
from harmful pathogenic invaders. Various types of immune cells collaborate in response to …
The Critical Role of NAC1 in Triple-Negative Breast Cancer Stemness and Immunosuppression
C Ngule - 2024 - search.proquest.com
Triple-negative breast cancer (TNBC) is a highly heterogeneous and the most lethal breast
cancer (BC) subtype. We report here a new role of nucleus accumbens associated protein 1 …
cancer (BC) subtype. We report here a new role of nucleus accumbens associated protein 1 …