Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease
SM de la Monte - Current Alzheimer Research, 2012 - ingentaconnect.com
Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …
30+ years of intense investigation, the field lacks consensus regarding the etiology and …
Neuroprotective and neurotrophic actions of glucagon‐like peptide‐1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders
I Salcedo, D Tweedie, Y Li… - British journal of …, 2012 - Wiley Online Library
Like type‐2 diabetes mellitus (T2DM), neurodegenerative disorders and stroke are an ever
increasing, health, social and economic burden for developed Westernized countries. Age is …
increasing, health, social and economic burden for developed Westernized countries. Age is …
Biomaterials for personalized cell therapy
Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …
treatments for previously intractable diseases. Notable examples include mesenchymal …
Teratomas from pluripotent stem cells: a clinical hurdle
CY Fong, K Gauthaman… - Journal of cellular …, 2010 - Wiley Online Library
Although basic research on human embryonic stem cells (hESCs) at the laboratory bench
has progressed with enviable speed there has been little head way in terms of its clinical …
has progressed with enviable speed there has been little head way in terms of its clinical …
Hippocampal GLP-1 receptors influence food intake, meal size, and effort-based responding for food through volume transmission
Abstract Glucagon-like peptide-1 (GLP-1) is produced in the small intestines and in nucleus
tractus solitarius (NTS) neurons. Activation of central GLP-1 receptors (GLP-1Rs) reduces …
tractus solitarius (NTS) neurons. Activation of central GLP-1 receptors (GLP-1Rs) reduces …
Mesenchymal stem cells in the treatment of traumatic brain injury
Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the
brain due to an injury following a trauma, which can potentially cause severe physical …
brain due to an injury following a trauma, which can potentially cause severe physical …
Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury
Traumatic brain injury is one of the leading causes of accidental death and disability. The
loss of parts in a severely injured brain induces edema, neuronal apoptosis, and …
loss of parts in a severely injured brain induces edema, neuronal apoptosis, and …
Application of cell encapsulation for controlled delivery of biological therapeutics
Cell microencapsulation technology is likely to have an increasingly important role in new
approaches rather than the classical and pioneering organ replacement. Apart from …
approaches rather than the classical and pioneering organ replacement. Apart from …
GLP-1's role in neuroprotection: a systematic review
D Erbil, CY Eren, C Demirel, MU Küçüker, I Solaroğlu… - Brain injury, 2019 - Taylor & Francis
ABSTRACT Glucagon-like peptide 1 (GLP-1) is a target for treatment of diabetes; however,
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …
Distribution of mesenchymal stem cells and effects on neuronal survival and axon regeneration after optic nerve crush and cell therapy
LA Mesentier-Louro, C Zaverucha-do-Valle… - PLoS …, 2014 - journals.plos.org
Bone marrow-derived cells have been used in different animal models of neurological
diseases. We investigated the therapeutic potential of mesenchymal stem cells (MSC) …
diseases. We investigated the therapeutic potential of mesenchymal stem cells (MSC) …