Whole-cell biocatalysts provide unique advantages and have been widely used for the
efficient biosynthesis of value-added fine and bulk chemicals, as well as pharmaceutically …

The concept of using amide bond distortion to modulate amidic resonance has been known
for more than 75 years. Two classic twisted amides (bridged lactams) ingeniously designed …

Performing one‐pot multi‐catalysis reactions is a revolutionary tool for multistep synthesis,
representing a fast‐developing theme in catalysis field. To develop cascade reactions …

Flavoprotein monooxygenases create valuable compounds that are of high interest for the
chemical, pharmaceutical, and agrochemical industries, among others. Monooxygenases …

Alcohol dehydrogenases (ADHs) catalyze the reversible reduction of a carbonyl group to its
corresponding alcohol. ADHs are widely employed for organic synthesis due to their lack of …

Artificial cascade reactions involving biocatalysts have demonstrated a tremendous potential
during the recent years. This review just focuses on selected examples of the last year and …

Enantiopure organic compounds are of major importance for the chemical and
pharmaceutical industry. Flavin‐dependent group E monooxygenases, composed of …

Alcohol dehydrogenases can act as powerful catalysts in the preparation of optically pure γ‐
hydroxy‐δ‐lactones by means of an enantioconvergent dynamic redox isomerization of …

Styrene monooxygenases (SMOs) are excellent enzymes for the production of (S)-
enantiopure epoxides, but so far, only one (R)-selective SMO has been identified with a …

Styrene monooxygenases (SMOs) are two-component enzymes known to catalyze the
epoxidation of styrene to (S)-styrene oxide. In this work, we identified a new oxygenase …