Management of acne vulgaris: a review

DZ Eichenfield, J Sprague, LF Eichenfield - Jama, 2021 - jamanetwork.com
Importance Acne vulgaris is an inflammatory disease of the pilosebaceous unit of the skin
that primarily involves the face and trunk and affects approximately 9% of the population …

The prevalence, risk factors, and psychosocial impacts of acne vulgaris in medical students: a literature review

M Sachdeva, J Tan, J Lim, M Kim… - International Journal …, 2021 - Wiley Online Library
Abstract Affecting approximately 9.4% of the population worldwide, acne vulgaris is a
common chronic inflammatory skin disease. Medical students are exposed to higher levels …

Isotretinoin and adverse neuropsychiatric outcomes: retrospective cohort study using routine data

T Paljarvi, T McPherson, S Luciano… - British Journal of …, 2022 - academic.oup.com
Background Severe neuropsychiatric outcomes have been reported in individuals exposed
to isotretinoin, but the evidence is inconclusive and complicated by several methodological …

Risk of Suicide and psychiatric disorders among isotretinoin users: a meta-analysis

NKW Tan, A Tang, NCYL MacAlevey, BKJ Tan… - JAMA …, 2024 - jamanetwork.com
Importance Isotretinoin is hypothesized to contribute to the development of psychiatric
disorders, but the epidemiological association and risk factors associated with psychiatric …

Isotretinoin laboratory monitoring in acne treatment: a Delphi consensus study

E Xia, J Han, A Faletsky, H Baldwin… - JAMA …, 2022 - jamanetwork.com
Importance Although isotretinoin may rarely be associated with laboratory abnormalities
such as hypertriglyceridemia, the optimal approach to laboratory monitoring is uncertain …

Challenges and solutions in oral isotretinoin in acne: reflections on 35 years of experience

V Bettoli, A Guerra-Tapia, MI Herane… - Clinical, cosmetic and …, 2019 - Taylor & Francis
Acne vulgaris affects more than 80% of adolescents and young adults and forms a
substantial proportion of the dermatologist's and general practitioner's caseload. Severity of …

[HTML][HTML] Isotretinoin and neuropsychiatric side effects: continued vigilance is needed

JD Bremner - Journal of affective disorders reports, 2021 - Elsevier
Abstract Background Isotretinoin (13-cis-retinoic acid, marketed under the names Accutane,
Roaccutane, and others) is an effective treatment for acne that has been on the market for …

Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

BL Mitchell, JR Saklatvala, N Dand… - Nature …, 2022 - nature.com
Acne vulgaris is a highly heritable skin disorder that primarily impacts facial skin. Severely
inflamed lesions may leave permanent scars that have been associated with long-term …

New acne therapies and updates on use of spironolactone and isotretinoin: a narrative review

JJ Han, A Faletsky, JS Barbieri, A Mostaghimi - Dermatology and therapy, 2021 - Springer
Acne vulgaris is a chronic inflammatory skin disease with a multifactorial pathogenesis.
Although a variety of acne treatments are available, limitations of current therapies include …

Risk of psychiatric disorders in patients taking isotretinoin: a nationwide, population-based, cohort study in Taiwan

YH Chen, WM Wang, CH Chung, CH Tsao… - Journal of Affective …, 2022 - Elsevier
Background After isotretinoin's approval to treat patients with recalcitrant acne, there have
been continued debates around its psychiatric safety profile. This study aimed to assess the …