Advances in photodynamic antimicrobial chemotherapy

A Anas, J Sobhanan, KM Sulfiya, C Jasmin… - … of Photochemistry and …, 2021 - Elsevier
Photodynamic therapy (PDT) and photodynamic antimicrobial chemotherapy (PACT)
combine light and photosensitizers to treat cancers and microbial infections, respectively. In …

Photodynamic disinfection and its role in controlling infectious diseases

RT Aroso, FA Schaberle, LG Arnaut… - Photochemical & …, 2021 - Springer
Photodynamic therapy is witnessing a revival of its origins as a response to the rise of multi-
drug resistant infections and the shortage of new classes of antibiotics. Photodynamic …

Translational feasibility and efficacy of nasal photodynamic disinfection of SARS-CoV-2

L Pires, BC Wilson, R Bremner, A Lang, J Larouche… - Scientific reports, 2022 - nature.com
The lack of therapeutic options to fight Covid-19 has contributed to the current global
pandemic. Despite the emergence of effective vaccines, development of broad-spectrum …

Chitosan-based drug delivery systems for optimization of photodynamic therapy: a review

GMF Calixto, SR de Annunzio, FD Victorelli… - Aaps Pharmscitech, 2019 - Springer
Drug delivery systems (DDS) can be designed to enrich the pharmacological and
therapeutic properties of several drugs. Many of the initial obstacles that impeded the clinical …

New applications of photodynamic therapy in the management of candidiasis

C Rodriguez-Cerdeira, E Martinez-Herrera… - Journal of Fungi, 2021 - mdpi.com
The most important aetiological agent of opportunistic mycoses worldwide is Candida spp.
These yeasts can cause severe infections in the host, which may be fatal. Isolates of …

Comparison of the efficacy of indocyanine green-mediated photodynamic therapy and nystatin therapy in treatment of denture stomatitis

B Afroozi, K Zomorodian, F Lavaee… - Photodiagnosis and …, 2019 - Elsevier
Background Candida species have an influence in the pathogenesis of denture stomatitis.
The current study aimed to investigate the efficacy of indocyanine green (ICG)-mediated …

Antimicrobial formulation of a bacterial nanocellulose/propolis-containing photosensitizer for biomedical applications

IS Gonçalves, LR Lima, AA Berretta, NA Amorim… - Polymers, 2023 - mdpi.com
With the aim of contributing to the development of more efficient materials for wound care,
new topical formulations based on bacterial nanocellulose (BNC) hydrogels containing …

Antimicrobial photodynamic therapy mediated by curcumin-loaded polymeric nanoparticles in a murine model of oral candidiasis

VT Sakima, PA Barbugli, PS Cerri, M Chorilli… - Molecules, 2018 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has been proposed as an alternative method for
oral candidiasis (OC), while nanocarriers have been used to improve the water solubility of …

Dual-agent photodynamic therapy with optical clearing eradicates pigmented melanoma in preclinical tumor models

L Pires, V Demidov, BC Wilson, AG Salvio, L Moriyama… - Cancers, 2020 - mdpi.com
Treatment using light-activated photosensitizers (photodynamic therapy, PDT) has shown
limited efficacy in pigmented melanoma, mainly due to the poor penetration of light in this …

Controlling methylene blue aggregation: a more efficient alternative to treat Candida albicans infections using photodynamic therapy

GA da Collina, F Freire, TPC Santos… - Photochemical & …, 2018 - Springer
Methylene Blue (MB) has been widely used in antimicrobial Photodynamic Therapy (aPDT),
however, the mechanisms of action (Type I or Type II) are defined by its state of aggregation …