Phytochemical constituents, bioactivities, and applications of custard apple (Annona squamosa L.): A narrative review

AY Moussa, SA Siddiqui, EA Elhawary, K Guo, S Anwar… - Food Chemistry, 2024 - Elsevier
Annona squamosa L.(Annonaceae) is a versatile tree with an edible fruit showing abundant
medicinal and industrial applications. The nutritional values of this plant are due to …

NLRP3 inflammasome and pyroptosis in liver pathophysiology: The emerging relevance of Nrf2 inducers

L Hurtado-Navarro, D Angosto-Bazarra, P Pelegrín… - Antioxidants, 2022 - mdpi.com
Inflammasomes, particularly the nucleotide-binding oligomerization domain, leucine-rich
repeat, and pyrin domain containing 3 (NLRP3) inflammasome, apparently serve as crucial …

Therapeutic promises of medicinal plants in Bangladesh and their bioactive compounds against ulcers and inflammatory diseases

SR Ahmed, MF Rabbee, A Roy, R Chowdhury, A Banik… - Plants, 2021 - mdpi.com
When functioning properly, the stomach is the center of both physical and mental
satisfaction. Gastrointestinal disorders, or malfunctioning of the stomach, due to infections …

Flavonoid epimers from custard apple leaves, a rapid screening and separation by HSCCC and their antioxidant and hypoglycaemic activities evaluation

H Zhu, L Chen, J Yu, L Cui, I Ali, X Song, JH Park… - Scientific reports, 2020 - nature.com
Leaves of custard apple are widely used in many places as a popular dietary supplement for
the treatment of diabetes. Flavonoids are known to have anti-diabetic activity. In this study …

Medicinal herbs and their metabolites with biological potential to protect and combat liver toxicity and its disorders: A review

SI Shawon, RN Reyda, N Qais - Heliyon, 2024 - cell.com
The liver is an essential organ that helps the body with immunity, metabolism, and
detoxification, among other functions. Worldwide, liver illnesses are a leading cause of …

Natural products, extracts and formulations comprehensive therapy for the improvement of motor function in alcoholic liver disease

S Hu, S Li, Q Yan, X Hu, L Li, H Zhou, L Pan, J Li… - Pharmacological …, 2019 - Elsevier
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide that afflicts
human health. With the in-depth study of the disease, its pathogenesis has gradually …

Bilobalide attenuates lipopolysaccharide‑induced HepG2 cell injury by inhibiting TLR4‑NF‑κB signaling via the PI3K/Akt pathway

S Mao, J Yao, T Zhang, X Zhang… - Experimental and …, 2023 - spandidos-publications.com
Inflammation is involved in the pathological process underlying a number of liver diseases.
Bilobalide (BB) is a natural compound from Ginkgo biloba leaves that was recently …

Hepatoprotective effects of fruits pulp, seed, and peel against chemical-induced toxicity: insights from in vivo studies

H Kumar, DS Dhanjal, S Guleria, E Nepovimova… - Food and Chemical …, 2024 - Elsevier
The liver is a vital organ in human physiology positioned in the upper right quadrant of the
peritoneal cavity, which plats a critical role in metabolic processes, detoxification of various …

Comparison between Annona squamosa, Annona cherimolia and Annona atemoya ethanolic extracts extenuative impact against oxidative stress, inflammation and …

A Abd-Elrazek, H Shapana, W Shukry… - Toxicology …, 2021 - academic.oup.com
Up-regulation of NF-kB and depletion of glutathione are acceptable mechanisms of
Ifosfamide (IFO) renal toxicity. This investigation elucidates the role of free radicals …

Protective Effects of Honey‐Processed Astragalus on Liver Injury and Gut Microbiota in Mice Induced by Chronic Alcohol Intake

J Zhou, N Zhang, L Zhao… - Journal of Food …, 2022 - Wiley Online Library
Honey‐processed Astragalus (HPA) is a mixture of Astragalus and honey, which is a
processed product of Chinese medicine. It has the active ingredients of Astragalus and the …