Transdermal patches are now widely used as cosmetic, topical and transdermal delivery
systems. These patches represent a key outcome from the growth in skin science …

Cells die by a variety of mechanisms. Terminally differentiated cells such as neurones die in
a variety of disorders, in part, via parthanatos, a process dependent on the activity of poly …

Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb, http://www.
guidetopharmacology. org) provides expert-curated molecular interactions between …

Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-
coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian …

Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …

Lysophospholipids encompass a diverse range of small, membrane‐derived phospholipids
that act as extracellular signals. The signalling properties are mediated by 7 …

As expenditure on drug development increases exponentially, the overall drug discovery
process requires a sustainable revolution. Since artificial intelligence (AI) is leading the …

Cannabigerol (CBG) is a safe non-psychotropic Cannabis-derived cannabinoid (CB), which
interacts with specific targets involved in carcinogenesis. Specifically, CBG potently blocks …

The endogenous cannabinoid signalling system, composed of endogenous cannabinoids,
cannabinoid receptors and the enzymes that synthesize and degrade the endogenous …

Pharmacological response depends on multiple factors and one of them is sex–gender.
Data on the specific effects of sex–gender on pharmacokinetics, as well as the safety and …