Fifteen years ago, cell lineage restriction boundaries were discovered in the embryonic
vertebrate hindbrain, subdividing it into a series of cell-tight compartments (known as …

MRI is a useful tool to complement US for imaging of the fetal posterior fossa (PF). In France,
the discovery of a PF malformation in the fetus frequently leads to termination of pregnancy …

Localized sources of morphogens, called signalling centres, play a fundamental role in
coordinating tissue growth and cell fate specification during organogenesis. However, how …

Brain structures derived from the mesencephalon (mes) and rhombomere 1 (r1) modulate
distinct motor and sensory modalities. The precise origin and cellular behaviors …

We applied single-cell RNA sequencing to profile genome-wide gene expression in about
9400 individual cerebellar cells from the mouse embryo at embryonic day 13.5. Reiterative …

During embryogenesis, the isthmic organizer, a well-described signaling center at the
junction of the mid-hindbrain, establishes the cerebellar territory along the anterior/posterior …

Lampreys are a key species to study the evolution of morphological characters at the dawn
of Craniates and throughout the evolution of the craniate's phylum. Here, we review a …

The cerebellum is a pivotal centre for the integration and processing of motor and sensory
information. Its extended development into the postnatal period makes this structure …

Choroid plexus (CP) produces the cerebrospinal fluid (CSF) of the central nervous system
(CNS), but little is known about the mechanisms underlying development of this important …

Despite its tremendous complexity, the vertebrate nervous system emerges from a
homogenous layer of neuroepithelial cells, the neural plate. Its formation relies on the time …