Not all nebulizers are created equal: Considerations in choosing a nebulizer for aerosol delivery during mechanical ventilation

R MacLoughlin, I Martin-Loeches - Expert Review of Respiratory …, 2023 - Taylor & Francis
Introduction Aerosol therapy is commonly prescribed in the mechanically ventilated patient.
Jet nebulizers (JN) and vibrating mesh nebulizers (VMN) are the most common nebulizer …

Nebuliser therapy in critical care: The past, present and future

A Arnott, M Watson, M Sim - Journal of The Intensive Care …, 2024 - journals.sagepub.com
Nebulisers are devices that reduce a body of liquid into a fine aerosol suitable for inhalation.
Utilising the efficiency of pulmonary drug absorption, they offer a safe and powerful modality …

Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support

J Li, K Liu, S Lyu, G Jing, B Dai, R Dhand, HL Lin… - Annals of intensive …, 2023 - Springer
Background Clinical practice of aerosol delivery in conjunction with respiratory support
devices for critically ill adult patients remains a topic of controversy due to the complexity of …

Pulmonary targeting of inhalable moxifloxacin microspheres for effective management of tuberculosis

B Vishwa, A Moin, DV Gowda, SMD Rizvi… - Pharmaceutics, 2021 - mdpi.com
In the present study, the objective was to attain a localized lung delivery of an anti-tubercular
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …

Inhaled drug delivery: a randomized study in intubated patients with healthy lungs

J Dugernier, D Le Pennec, G Maerckx… - Annals of intensive …, 2023 - Springer
Background The administration technique for inhaled drug delivery during invasive
ventilation remains debated. This study aimed to compare in vivo and in vitro the deposition …

The influence of changing interfaces on aerosol delivery within high flow oxygen setting in adults: an in-vitro study

YM Madney, NI Laz, AA Elberry, H Rabea… - Journal of Drug Delivery …, 2020 - Elsevier
Despite the fact that the nasal-cannula is more comfortable than facemask, using facemask
with high flow oxygen therapy (HFOT) may be beneficial in mouth-breathers. The aim of the …

Effects of fill volume and humidification on aerosol delivery during single-limb noninvasive ventilation

H Saeed, M Mohsen, AS Eldin, AA Elberry… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: The aim of this work was to determine the effect of fill volume and
humidification change on aerosol delivery during single-limb noninvasive ventilation (NIV) …

Modeling and optimization of nebulizers' performance in non-invasive ventilation using different fill volumes: comparative study between vibrating mesh and jet …

H Saeed, AMA Ali, AA Elberry, AS Eldin… - Pulmonary …, 2018 - Elsevier
Backgrounds Substituting nebulisers by another, especially in non-invasive ventilation (NIV),
involves many process-variables, eg nebulizer-type and fill-volume of respirable-dose …

Performance of large spacer versus nebulizer T-piece in single-limb noninvasive ventilation

HS Harb, AA Elberry, H Rabea, M Fathy… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: Predosing patients with COPD with salbutamol by using a pressurized
metered-dose-inhaler (pMDI) as a bronchodilator was hypothesized to improve the …

Effect of age of COVID‐19 inpatient on the severity of the disease: a meta‐analysis

S Chai, Y Li, X Li, J Tan… - International Journal of …, 2021 - Wiley Online Library
Background Clinical symptoms of adults and paediatric inpatients with COVID‐19 disease
are conflicting. This meta‐analysis was conducted to assess the effect of age of COVID‐19 …