[HTML][HTML] QSAR analysis of the toxicity of phenols and thiophenols using MLR and ANN

M Ghamali, S Chtita, A Ousaa, B Elidrissi… - Journal of Taibah …, 2017 - Elsevier
This study gives a quantitative structure–activity relationship (QSAR) analysis of toxicity of
phenols and thiophenols to Photobacterium phosphoreum, which is an important indicator …

[HTML][HTML] The inhibitory activity of aldose reductase of flavonoid compounds: Combining DFT and QSAR calculations

M Ghamali, S Chtita, R Hmamouchi, A Adad… - Journal of Taibah …, 2016 - Elsevier
Abstract The DFT-B3LYP method, with the base set 6-31G (d), was used to calculate several
quantum chemical descriptors of 44 substituted flavonoids. The best descriptors were …

2D-QSAR study and design of novel pyrazole derivatives as an anticancer lead compound against A-549, MCF-7, HeLa, HepG-2, PaCa-2, DLD-1

FE Bennani, L Doudach, K Karrouchi, CE Rudd… - Computational …, 2023 - Elsevier
In this study, a local quantitative structure–activity relationship (QSAR) models were
developed for set of compounds tested for their inhibitory activity against six different cancer …

Density Functional Theory (DFT) Study on the Nontoxic Alternative of Bisphenol A (BPA) Derivatives: A Comprehensive Review

P Agarwal, A Kumar - Macromolecular Symposia, 2024 - Wiley Online Library
Bisphenol A is an oil‐derived, large market volume chemical with a wide spectrum of
applications in plastics, adhesives, and thermal papers. However, bisphenol A and its …

[PDF][PDF] Quantitative structure-toxicity relationship studies of aromatic aldehydes to Tetrahymena pyriformis based on electronic and topological descriptors

A Ousaa, B Elidrissi, M Ghamali, S Chtita… - J. Mater …, 2018 - jmaterenvironsci.com
To establish a quantitative structure-toxicity relationship (QSTR) of a series of 77 aromatic
aldehydes for their acute toxicity against Tetrahymena pyriformis, were used the principal …

QSAR and docking studies on the pyrimidine derivatives analogs with antileishmanial activity

A Ousaa - RHAZES: Green and Applied Chemistry, 2018 - revues.imist.ma
Leishmaniasis is a disease caused by a number of species of protozoan parasites
belonging to the genus Leishmania, is recognized as an important public health problem …

Quantitative structure-activity relationships; studying the toxicity of metal nanoparticles

Y Gao, H Zhai, X She, H Si - Current Topics in Medicinal …, 2020 - ingentaconnect.com
Background: Metal nanomaterials are widely used in various fields, including targeted
therapy and diagnosis. They are extensively used in targeted drug delivery and local …

QSAR Study of (5‐Nitroheteroaryl‐1, 3, 4‐Thiadiazole‐2‐yl) Piperazinyl Derivatives to Predict New Similar Compounds as Antileishmanial Agents

A Ousaa, B Elidrissi, M Ghamali, S Chtita… - Advances in …, 2018 - Wiley Online Library
To search for newer and potent antileishmanial drugs, a series of 36 compounds of 5‐(5‐
nitroheteroaryl‐2‐yl)‐1, 3, 4‐thiadiazole derivatives were subjected to a quantitative …

[PDF][PDF] QSTR analysis and combining DFT of the toxicity of heterogeneous phenols

A Ousaa, B Elidrissi, M Ghamali, S Chtita… - J. Mater …, 2017 - jmaterenvironsci.com
Quantitative structure–toxicity relationship (QSTR) models are useful to understand how
chemical structure relates to the toxicity of natural and synthetic chemicals. The chemical …

Quantitative Structure–Activity Relationship (QSAR) Studies of Some Glutamine Analogues for Possible Anticancer Activity

B Elidrissi, A Ousaa, M Ghamali, S Chtita… - Moroccan Journal of …, 2018 - revues.imist.ma
Abstract A Quantitative Structure–Activity Relationship (QSAR) study was performed to
predict an anticancer activity in tumor cells of thirty-six 5-N-substituted-2-(substituted …