Scrapie, an invariably fatal disease of sheep and goats, is a transmissible spongiform
encephalopathy (TSE). The putative infectious agent is the host-encoded prion protein, PrP …

Scrapie, bovine spongiform encephalopathy (BSE), and chronic wasting disease (CWD) are
prion diseases in ruminants with considerable impact on animal health and welfare. They …

The association between PrP gene variations and scrapie susceptibility was studied in a
single herd of Ionica breed goats. The entire herd comprised 100 animals, 11 of which were …

Background The development of active surveillance programmes for transmissible
spongiform encephalopathies of small ruminants across Europe has led to the recent …

The Rasa Aragonesa sheep is the second most important Spanish breed after the Merino
breed. Reported here is the prion protein (PrP) haplotype frequency distribution for scrapie …

Prions are proteins that play a central role in transmissible spongiform encephalopathies in
a variety of mammals. Among the most notable prion disorders in ungulates are scrapie in …

A total of 216 local crossbred sheep from 16 scrapie-affected Greek flocks and 210 purebred
sheep of the milk breeds Chios and Karagouniko from healthy flocks were analysed for …

Small ruminants, including sheep and goats are natural hosts of scrapie, and the
progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion …

Aims: To analyse the frequencies of prion (PrP) gene haplotypes in UK sheep flocks and
evaluate their relevance to transmissible spongiform encephalopathies (TSEs) and TSE …

Breeding programmes to promote resistance to classical scrapie, similar to those for sheep
in existing transmissible spongiform encephalopathies (TSE) regulations, have not been …