Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

Mitochondrial dysfunction in neurons has recently become a promising therapeutic target for
Alzheimer's disease (AD). Regulation of dysfunctional mitochondria through multiple …

FGFs (fibroblast growth factors) and their receptors (FGFRs) play essential roles in tightly
regulating cell proliferation, survival, migration and differentiation during development and …

Fibroblast growth factor (FGF) 23 is a phosphaturic hormone whose physiologic actions on
target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co …

Cell migration and invasion are critical parameters in the metastatic dissemination of cancer
cells and the formation of metastasis, the major cause of death in cancer patients. Migratory …

Fibroblast growth factors (FGFs) act as key signalling molecules in brain development,
maintenance, and repair. They influence the intricate relationship between myelinating cells …

Our understanding of endocytosis has evolved remarkably in little more than a decade. This
is the result not only of advances in our knowledge of its molecular and biological workings …

Fibroblast growth factor (FGF) signaling regulates cell proliferation, differentiation, survival,
angiogenesis, and wound healing. Compelling evidence for deregulated FGF signaling in …

Increasing evidence indicates that success of targeted therapies in the treatment of cancer is
context-dependent and is influenced by a complex crosstalk between signaling pathways …