Clinical characterization of Lassa fever: A systematic review of clinical reports and research to inform clinical trial design

L Merson, J Bourner, S Jalloh, A Erber… - PLOS Neglected …, 2021 - journals.plos.org
Background Research is urgently needed to reduce the morbidity and mortality of Lassa
fever (LF), including clinical trials to test new therapies and to verify the efficacy and safety of …

Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments

HL Murphy, H Ly - Virulence, 2021 - Taylor & Francis
Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …

Modelling the transmission dynamics of Lassa fever with nonlinear incidence rate and vertical transmission

A Abidemi, KM Owolabi, E Pindza - Physica A: Statistical Mechanics and its …, 2022 - Elsevier
In this paper, a seven-dimensional nonlinear mathematical model featuring the vertical
transmission in humans, saturated incidence functions, and human population with good …

Lassa fever in pregnancy: a systematic review and meta-analysis

ND Kayem, C Benson, CYL Aye… - Transactions of the …, 2020 - academic.oup.com
Lassa fever is a zoonotic infection endemic to West Africa and is known to have adverse
effects in pregnancy. We sought to synthesize and critically appraise currently available …

Epidemiology of Lassa fever

AR Bell-Kareem, AR Smither - Lassa Fever: Epidemiology, Immunology …, 2021 - Springer
Lassa fever (LF) is a lethal hemorrhagic disease primarily concentrated in the tropical
savannah regions of Nigeria and the Mano River Union countries of Sierra Leone, Liberia …

Common pathways targeted by viral hemorrhagic fever viruses to infect the placenta and increase the risk of stillbirth

B Coler, O Cervantes, M Li, C Coler, A Li… - Placenta, 2023 - Elsevier
Viral hemorrhagic fevers (VHF) are endemic to Africa, South America and Asia and
contribute to significant maternal and fetal morbidity and mortality. Viruses causing VHFs are …

Recent updates on research models and tools to study virus–host interactions at the placenta

JK Lee, SJ Oh, H Park, OS Shin - Viruses, 2019 - mdpi.com
The placenta is a unique mixed organ, composed of both maternal and fetal tissues, that is
formed only during pregnancy and serves as the key physiological and immunological …

Understanding immune responses to Lassa virus infection and to its candidate vaccines

H Murphy, H Ly - Vaccines, 2022 - mdpi.com
Lassa fever (LF) is a deadly viral hemorrhagic fever disease that is endemic in several
countries in West Africa. It is caused by Lassa virus (LASV), which has been estimated to be …

Public health response to two imported, epidemiologically related cases of Lassa fever in the Netherlands (ex Sierra Leone), November 2019

F Overbosch, M de Boer, KE Veldkamp… - …, 2020 - eurosurveillance.org
On 20 November 2019, Lassa fever was diagnosed in a physician repatriated from Sierra
Leone to the Netherlands. A second physician with suspected Lassa fever, repatriated a few …

Fatal case of newborn Lassa fever virus infection mimicking late onset neonatal sepsis: a case report from northern Nigeria

TO Ogunkunle, SO Bello, CI Anderson, R Musa… - Infectious Diseases of …, 2020 - Springer
Background Lassa fever is a zoonotic viral infection endemic to the West Africa countries. It
is highly fatal during pregnancy and as such reports of neonatal onset Lassa fever infections …