The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …

With more than ten new FDA approvals since 2001, peptides are emerging as an important
therapeutic alternative to small molecules. However, unlike small molecules, peptides on the …

The innate immune system utilizes many approaches for defense against invading
microorganisms, including complement-mediated lysis, engulfment, formation of neutrophil …

Recently, much attention has been given to the problem of drug delivery through the cell‐
membrane in order to treat and manage several diseases. The discovery of cell penetrating …

With the rapid rise in the emergence of bacterial strains resistant to multiple classes of
antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to …

ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …

In this study, the use of cubosomes for topical delivery of the antimicrobial peptide (AMP) LL-
37 was investigated. Topical delivery of AMPs is of great interest for treatment of skin …

Antimicrobial peptides are diverse group of biologically active molecules with
multidimensional properties. In recent past, a wide variety of AMPs with diverse structures …

Antimicrobial peptides are small molecules with activity against bacteria, yeasts, fungi,
viruses, bacteria, and even tumor cells that make these molecules attractive as therapeutic …