Identification of cancer stem cell-related genes through single cells and machine learning for predicting prostate cancer prognosis and immunotherapy
YX Wang, L Ma, J He, HJ Gu, HX Zhu - Frontiers in Immunology, 2024 - frontiersin.org
Background Cancer stem cells (CSCs) are a subset of cells within tumors that possess the
unique ability to self-renew and give rise to diverse tumor cells. These cells are crucial in …
unique ability to self-renew and give rise to diverse tumor cells. These cells are crucial in …
Functions of CAFs in microenvironment of non-small cell lung cancer: based on updated hallmarks of cancer
X Feng, B Zhu, Y Peng, K Zhang, Y Wang, G Huang… - Oncologie, 2024 - degruyter.com
Non-small cell lung cancer (NSCLC) is the most common subtype of lung cancer, which
ranks as the first malignant tumor in mortality. The occurrence and development of NSCLC …
ranks as the first malignant tumor in mortality. The occurrence and development of NSCLC …
Integrative Analysis and Validation of a Cancer-associated Fibroblasts Senescence-related Signature for Risk Stratification and Therapeutic Prediction in Esophageal …
H Zhang, K Hong, Q Song, B Zhu, G Wu… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Cellular senescence is closely associated with cancer development and progression. There
is ample evidence that tumor stromal cells, especially cancer-associated fibroblasts (CAFs) …
is ample evidence that tumor stromal cells, especially cancer-associated fibroblasts (CAFs) …
RNA-seq and bulk RNA-seq data analysis of cancer-related fibroblasts (CAF) in LUAD to construct a CAF-based risk signature
Y Si, Z Zhao, X Meng, K Zhao - Scientific Reports, 2024 - nature.com
Angiogenesis, metastasis, and resistance to therapy are all facilitated by cancer-associated
fibroblasts (CAFs). A CAF-based risk signature can be used to predict patients' prognoses …
fibroblasts (CAFs). A CAF-based risk signature can be used to predict patients' prognoses …
单细胞RNA 测序技术在肺癌肿瘤微环境研究中的进展
W Yanhong, LUO Bin, W Zhuo… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
免疫微环境对肿瘤的发生发展起着关键作用. 近年来, 随着高通量测序技术的飞速发展,
研究人员对肿瘤微环境中的免疫细胞组成及其功能有了更深入的了解. 然而 …
研究人员对肿瘤微环境中的免疫细胞组成及其功能有了更深入的了解. 然而 …
[HTML][HTML] GINS1 通过激活Notch/PI3K/AKT/mTORC1 信号通路增强肺腺癌细胞糖酵解, 增殖和转移
HUO Yishan, XU Xiaohui, MA Xiumin… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
背景与目的肺癌是所有癌症类型中占比最大的一种, 其中肺腺癌(lung adenocarcinoma, LUAD)
占肺癌患者的一半以上. 目前, 转移性LUAD 患者5 年生存率仍然较低, 迫切需要新型生物标志物 …
占肺癌患者的一半以上. 目前, 转移性LUAD 患者5 年生存率仍然较低, 迫切需要新型生物标志物 …
[HTML][HTML] Notch3 and Its Clinical Importance in Ovarian Cancer
Background: Ovarian cancer (OC) is the most prevalent gynecological malignancy in
women, often diagnosed at an advanced stage due to the absence of specific clinical …
women, often diagnosed at an advanced stage due to the absence of specific clinical …
[HTML][HTML] Identification of a gene expression signature of vascular invasion and recurrence in stage I lung adenocarcinoma via bulk and spatial transcriptomics
D Steiner, L Sultan, T Sullivan, H Liu, S Zhang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Microscopic vascular invasion (VI) is predictive of recurrence and benefit from lobectomy in
stage I lung adenocarcinoma (LUAD) but is difficult to assess in resection specimens and …
stage I lung adenocarcinoma (LUAD) but is difficult to assess in resection specimens and …
[PDF][PDF] 单细胞RNA 测序技术在肺癌肿瘤微环境研究中的进展
王衍鸿， 罗斌， 王卓， 阙祖俊， 蒋雷， 田建辉 - pdfs.semanticscholar.org
免疫微环境对肿瘤的发生发展起着关键作用. 近年来, 随着高通量测序技术的飞速发展,
研究人员对肿瘤微环境中的免疫细胞组成及其功能有了更深入的了解. 然而 …
研究人员对肿瘤微环境中的免疫细胞组成及其功能有了更深入的了解. 然而 …
Advancements in Single-cell RNA Sequencing Technology in the Study of the Tumor Microenvironment in Lung Cancer.
W Yanhong, LUO Bin, W Zhuo… - Chinese Journal of …, 2024 - search.ebscohost.com
The immune microenvironment plays a key role in the development and progression of
tumors. In recent years, with the rapid advancement of high-throughput sequencing …
tumors. In recent years, with the rapid advancement of high-throughput sequencing …