Of chloroquine and COVID-19

F Touret, X de Lamballerie - Antiviral research, 2020 - Elsevier
Recent publications have brought attention to the possible benefit of chloroquine, a broadly
used antimalarial drug, in the treatment of patients infected by the novel emerged …

Chloroquine and hydroxychloroquine in the treatment of COVID-19 with or without diabetes: A systematic search and a narrative review with a special reference to …

AK Singh, A Singh, A Shaikh, R Singh… - Diabetes & Metabolic …, 2020 - Elsevier
Background and aims No drugs are currently approved for Coronavirus Disease-2019
(COVID-19), although some have been tried. In view of recent studies and discussion on …

Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self …

JCE Lane, J Weaver, K Kostka, T Duarte-Salles… - MedRxiv, 2020 - medrxiv.org
Background Hydroxychloroquine has recently received Emergency Use Authorization by the
FDA and is currently prescribed in combination with azithromycin for COVID-19 pneumonia …

[HTML][HTML] Chloroquine, an endocytosis blocking agent, inhibits Zika virus infection in different cell models

R Delvecchio, LM Higa, P Pezzuto, AL Valadão… - Viruses, 2016 - mdpi.com
Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects.
Since no specific therapy is available thus far, there is an urgent need for the discovery of …

Chloroquine and hydroxychloroquine in the treatment of COVID-19: the never-ending story

A Gasmi, M Peana, S Noor, R Lysiuk, A Menzel… - Applied microbiology …, 2021 - Springer
The anti-malarial drugs chloroquine (CQ) and hydroxychloroquine (HCQ) have been
suggested as promising agents against the new coronavirus SARS-CoV-2 that induces …

Drug repositioning: new approaches and future prospects for life-debilitating diseases and the COVID-19 pandemic outbreak

ZY Low, IA Farouk, SK Lal - Viruses, 2020 - mdpi.com
Traditionally, drug discovery utilises a de novo design approach, which requires high cost
and many years of drug development before it reaches the market. Novel drug development …

Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19

ZN Lei, ZX Wu, S Dong, DH Yang, L Zhang, Z Ke… - Pharmacology & …, 2020 - Elsevier
Abstract Chloroquine (CQ) and Hydroxychloroquine (HCQ) have been commonly used for
the treatment and prevention of malaria, and the treatment of autoimmune diseases for …

Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine

A Sarayani, B Cicali, CH Henriksen… - Research in Social and …, 2021 - Elsevier
Background Combinations of hydroxychloroquine (HCQ) and azithromycin have been
promoted as treatments for COVID-19 based on small, uncontrolled clinical trials that have …

[HTML][HTML] Clinical evidence for repurposing chloroquine and hydroxychloroquine as antiviral agents: a systematic review

C Rodrigo, SD Fernando, S Rajapakse - Clinical Microbiology and Infection, 2020 - Elsevier
Background Repurposing hydroxychloroquine (HCQ) and chloroquine (CQ) as antiviral
agents is a re-emerging topic with the advent of new viral epidemics. Aims To summarize …

The rise and fall of chloroquine/hydroxychloroquine as compassionate therapy of COVID-19

E Manivannan, C Karthikeyan… - Frontiers in …, 2021 - frontiersin.org
The emergence and rapid spread of novel coronavirus disease (COVID-19) has posed a
serious challenge to global public health in 2020. The speed of this viral spread together …