Cerebellar Purkinje cells exhibit a unique type of synaptic plasticity, namely, long-term
depression (LTD). When two inputs to a Purkinje cell, one from a climbing fiber and the other …

How the elaborate neuronal circuit in the cerebellum operates and is involved in motor
learning is a question addressed in earnest in studies on the cerebellum. During the past …

The persistence of many contrasting notions of climbing fiber function after years of
investigation testifies that the issue of climbing fiber contributions to cerebellar transactions …

The vestibulo–ocular reflex, because of its close relationship with the cerebellum and its
marked adaptiveness, has become a model system for studying the functions of the …

Kobayashi, Yasushi, Kenji Kawano, Aya Takemura, Yuka Inoue, Toshihiro Kitama, Hiroaki
Gomi, and Mitsuo Kawato. Temporal firing patterns of Purkinje cells in cerebellar ventral …

How Purkinje cell (PC) activity may be altered by learning is central to theories of the
cerebellum. Pavlovian eyelid conditioning, because of how directly it engages the …

The floccular lobe of the monkey is critical for the generation of visually-guided smooth eye
movements. The present experiments reveal physiological correlates of the directional …

We followed simple-and complex-spike firing of Purkinje cells (PCs) in the floccular complex
of the cerebellum through learned modifications of the pursuit eye movements of two …

Background: Falls and fractures due to impaired balance in patients with Alzheimer's
disease (AD) have an adverse effect on the clinical course of the disease. Objective: To …

The climbing fiber input to the cerebellum conveys instructive signals that can induce
synaptic plasticity and learning by triggering complex spikes accompanied by large calcium …