Shattering barriers toward clinically meaningful MSC therapies
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
[PDF][PDF] Mesenchymal stromal cell homing: mechanisms and strategies for improvement
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
Manufacturing of primed mesenchymal stromal cells for therapy
JQ Yin, J Zhu, JA Ankrum - Nature biomedical engineering, 2019 - nature.com
Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …
manufactured and developed as unique cell products by many different manufacturers and …
Mesenchymal stem cells: immune evasive, not immune privileged
The diverse immunomodulatory properties of mesenchymal stem/stromal cells (MSCs) may
be exploited for treatment of a multitude of inflammatory conditions. MSCs have long been …
be exploited for treatment of a multitude of inflammatory conditions. MSCs have long been …
[HTML][HTML] The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy
D García-Bernal, M García-Arranz… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …
advanced therapies with different purposes, most of which are related with inflammatory …
Recent progress of stem cell therapy in cancer treatment: molecular mechanisms and potential applications
The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …
MSCs: delivery routes and engraftment, cell‐targeting strategies, and immune modulation
Mesenchymal stem cells (MSCs) are currently being widely investigated both in the lab and
in clinical trials for multiple disease states. The differentiation, trophic, and …
in clinical trials for multiple disease states. The differentiation, trophic, and …
[PDF][PDF] Mesenchymal stem cell homing: the devil is in the details
The study of MSC trafficking is clinically relevant for minimally invasive cell therapy to
promote regeneration of damaged tissue, to treat inflammation, and to promote …
promote regeneration of damaged tissue, to treat inflammation, and to promote …
Recent advances in mesenchymal stem cell membrane-coated nanoparticles for enhanced drug delivery
Studies of nanomedicine have achieved dramatic progress in recent decades. However, the
main challenges that traditional nanomedicine has to overcome include low accumulation at …
main challenges that traditional nanomedicine has to overcome include low accumulation at …
[PDF][PDF] Glycotherapy: new advances inspire a reemergence of glycans in medicine
JE Hudak, CR Bertozzi - Chemistry & biology, 2014 - cell.com
The beginning of the 20 th century marked the dawn of modern medicine with glycan-based
therapies at the forefront. However, glycans quickly became overshadowed as DNA-and …
therapies at the forefront. However, glycans quickly became overshadowed as DNA-and …