Brain glucose metabolism: integration of energetics with function

GA Dienel - Physiological reviews, 2019 - journals.physiology.org
Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …

Diabetic polyneuropathy in type 2 diabetes mellitus: inflammation, oxidative stress, and mitochondrial function

LM Román-Pintos, G Villegas-Rivera… - Journal of diabetes …, 2016 - Wiley Online Library
Diabetic polyneuropathy (DPN) is defined as peripheral nerve dysfunction. There are three
main alterations involved in the pathologic changes of DPN: inflammation, oxidative stress …

Energy metabolism of the brain, including the cooperation between astrocytes and neurons, especially in the context of glycogen metabolism

A Falkowska, I Gutowska, M Goschorska… - International journal of …, 2015 - mdpi.com
Glycogen metabolism has important implications for the functioning of the brain, especially
the cooperation between astrocytes and neurons. According to various research data, in a …

[HTML][HTML] Diabetes mellitus and blood-brain barrier dysfunction: an overview

S Prasad, RK Sajja, P Naik… - Journal of …, 2014 - ncbi.nlm.nih.gov
A host of diabetes-related insults to the central nervous system (CNS) have been clearly
documented in type-1 and-2 diabetic patients as well as experimental animal models. These …

Taurine supplementation as a neuroprotective strategy upon brain dysfunction in metabolic syndrome and diabetes

Z Rafiee, AM García-Serrano, JMN Duarte - Nutrients, 2022 - mdpi.com
Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and
function and constitute risk factors for cognitive impairment. Alterations to taurine …

Neurochemical modifications in the hippocampus, cortex and hypothalamus of mice exposed to long-term high-fat diet

B Lizarbe, AF Soares, S Larsson… - Frontiers in …, 2019 - frontiersin.org
Metabolic syndrome and diabetes impact brain function and metabolism. While it is well
established that rodents exposed to diets rich in saturated fat develop brain dysfunction …

Antioxidant strategies in the management of diabetic neuropathy

AB Oyenihi, AO Ayeleso, E Mukwevho… - BioMed research …, 2015 - Wiley Online Library
Chronic hyperglycaemia (an abnormally high glucose concentration in the blood) resulting
from defects in insulin secretion/action, or both, is the major hallmark of diabetes in which it …

B0 shimming for in vivo magnetic resonance spectroscopy: Experts' consensus recommendations

C Juchem, C Cudalbu, RA de Graaf… - NMR in …, 2021 - Wiley Online Library
Magnetic resonance spectroscopy (MRS) and spectroscopic imaging (MRSI) allow the
chemical analysis of physiological processes in vivo and provide powerful tools in the life …

Brain metabolism alterations in type 2 diabetes: what did we learn from diet-induced diabetes models?

AM Garcia-Serrano, JMN Duarte - Frontiers in neuroscience, 2020 - frontiersin.org
Type 2 diabetes (T2D) is a metabolic disease with impact on brain function through
mechanisms that include glucose toxicity, vascular damage and blood–brain barrier (BBB) …

Bioactives of Momordica charantia as Potential Anti-Diabetic/Hypoglycemic Agents

B Xu, Z Li, T Zeng, J Zhan, S Wang, CT Ho, S Li - Molecules, 2022 - mdpi.com
Momordica charantia L., a member of the Curcubitaceae family, has traditionally been used
as herbal medicine and as a vegetable. Functional ingredients of M. charantia play …