Characterizing genes associated with cancer using the CRISPR/Cas9 system: A systematic review of genes and methodological approaches

The CRISPR/Cas9 system enables a versatile set of genomes editing and genetic-based
disease modeling tools due to its high specificity, efficiency, and accessible design and …

The molecular and pathophysiological functions of members of the LNX/PDZRN E3 ubiquitin ligase family

J Hong, M Won, H Ro - Molecules, 2020 - mdpi.com
The ligand of Numb protein-X (LNX) family, also known as the PDZRN family, is composed
of four discrete RING-type E3 ubiquitin ligases (LNX1, LNX2, LNX3, and LNX4), and LNX5 …

Comprehensive molecular profiling of pulmonary pleomorphic carcinoma

M Nagano, S Kohsaka, T Hayashi, T Ueno… - NPJ Precision …, 2021 - nature.com
Abstract Information regarding the molecular features of pulmonary pleomorphic carcinoma
(PPC) is insufficient. Here, we performed next-generation sequencing to determine the …

AMPK inhibitor, compound C, inhibits coronavirus replication in vitro

M Jang, R Park, A Yamamoto, YI Park, Y Park, S Lee… - Plos one, 2023 - journals.plos.org
The coronavirus disease (COVID-19) pandemic has resulted in more than six million deaths
by October 2022. Vaccines and antivirals for severe acute respiratory syndrome coronavirus …

t (4; 12)(q12; p13) ETV6-rearranged AML without eosinophilia does not involve PDGFRA: relevance for imatinib insensitivity

SB Mueller, P Dal Cin, LP Le… - Blood …, 2022 - ashpublications.org
Acute myeloid leukemia (AML) with t (4; 12)(q12; p13) translocation is rare and often
associated with an aggressive clinical course and poor prognosis. Previous reports based …

[HTML][HTML] Amentoflavone from Selaginella tamariscina inhibits SARS-CoV-2 RNA-dependent RNA polymerase

KW Youn, S Lee, JH Kim, YI Park, J So, C Kim, CW Cho… - Heliyon, 2024 - cell.com
The SARS-CoV-2 pandemic caused millions of deaths due to its prominent infectivity and
mortality. Although the vaccines and medicines for SARS-CoV-2 are on the market, new …

LNX1 Contributes to Cell Cycle Progression and Cisplatin Resistance

M Jang, R Park, YI Park, Y Park, JI Lee, S Namkoong… - Cancers, 2021 - mdpi.com
Simple Summary The ligand of numb-protein X1 (LNX1) is reported to be upregulated in
various cancers, however the cellular function of LNX1 is not clearly characterized. The aim …

Régulation par l'activité glycinergique des mécanismes cellulaires et moléculaires durant la neurogenèse embryonnaire

A Bekri - 2020 - papyrus.bib.umontreal.ca
Dans le système nerveux central adulte, la glycine est principalement connue pour son rôle
de transmission d'un signal inhibiteur à l'intérieur des neurones matures, régulant ainsi …