Molecular mechanisms of hepatocellular carcinoma

RN Aravalli, CJ Steer, ENK Cressman - Hepatology, 2008 - journals.lww.com
Hepatocellular carcinoma (HCC) typically has poor prognosis, because it is often diagnosed
at an advanced stage. Heterogeneous phenotypic and genetic traits of affected individuals …

The diverse roles and dynamic rearrangement of vimentin during viral infection

Y Zhang, Z Wen, X Shi, YJ Liu… - Journal of cell …, 2021 - journals.biologists.com
Epidemics caused by viral infections pose a significant global threat. Cytoskeletal vimentin is
a major intermediate filament (IF) protein, and is involved in numerous functions, including …

miR-221 overexpression contributes to liver tumorigenesis

P Pineau, S Volinia, K McJunkin… - Proceedings of the …, 2010 - National Acad Sciences
MicroRNA (miRNAs) are negative regulators of gene expression and can function as tumor
suppressors or oncogenes. Expression patterns of miRNAs and their role in the …

Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter

SO Lim, JM Gu, MS Kim, HS Kim, YN Park, CK Park… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS: In addition to genetic alterations, epigenetic changes underlie
tumor progression and metastasis. Promoter methylation can silence tumor suppressor …

[HTML][HTML] Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic …

SO Lim, SG Park, JH Yoo, YM Park, HJ Kim… - World journal of …, 2005 - ncbi.nlm.nih.gov
AIM: Expression of heat shock proteins (HSPs) is frequently up-regulated in hepatocellular
carcinoma (HCC), which evolves from dysplastic nodule (DN) and early HCC to advanced …

Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues

W Sun, B Xing, Y Sun, X Du, M Lu, C Hao, Z Lu… - Molecular & cellular …, 2007 - ASBMB
Hepatocellular carcinoma (HCC) is a highly malignant tumor, and chronic infection with
hepatitis B virus is one of its major risk factors. To identify the proteins involved in HCC …

Overexpression of alpha enolase in hepatitis C virus‐related hepatocellular carcinoma: association with tumor progression as determined by proteomic analysis

M Takashima, Y Kuramitsu, Y Yokoyama, N Iizuka… - …, 2005 - Wiley Online Library
To identify proteins that could be molecular targets for diagnosis and treatment of hepatitis C
virus‐related hepatocellular carcinoma (HCV‐related HCC), we used a proteomic approach …

[HTML][HTML] Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer

FR Jazii, Z Najafi, R Malekzadeh… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To assess the proteome of normal versus tumor tissue in squamous cell carcinoma of
the esophagus (SCCE) in Iranian patients and compare our results with former reports by …

Accurate qualitative and quantitative proteomic analysis of clinical hepatocellular carcinoma using laser capture microdissection coupled with isotope-coded affinity …

C Li, Y Hong, YX Tan, H Zhou, JH Ai, SJ Li… - Molecular & Cellular …, 2004 - ASBMB
Laser capture microdissection (LCM) is a powerful tool that enables the isolation of specific
cell types from tissue sections, overcoming the problem of tissue heterogeneity and …

[HTML][HTML] Growth rate of early-stage hepatocellular carcinoma in patients with chronic liver disease

C An, YA Choi, D Choi, YH Paik, SH Ahn… - Clinical and …, 2015 - ncbi.nlm.nih.gov
Methods Patients with early-stage HCC (n= 175) who underwent two or more serial dynamic
imaging studies without any anticancer treatment at two tertiary care hospitals in Korea were …