COVID-19-associated fungal infections
Abstract Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an
important complication in a substantial number of critically ill, hospitalized patients with …
important complication in a substantial number of critically ill, hospitalized patients with …
Innate immunity: the first line of defense against SARS-CoV-2
MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
Innate immune evasion strategies of SARS-CoV-2
JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
Structural biology of SARS-CoV-2: open the door for novel therapies
W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for
coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and …
coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and …
SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression
N Arshad, M Laurent-Rolle… - Proceedings of the …, 2023 - National Acad Sciences
Major histocompatibility complex class I (MHC-I) molecules, which are dimers of a
glycosylated polymorphic transmembrane heavy chain and the small-protein β2 …
glycosylated polymorphic transmembrane heavy chain and the small-protein β2 …
SARS-CoV-2 biology and host interactions
The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …
Roles and functions of SARS-CoV-2 proteins in host immune evasion
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades the host immune
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
Pathogenesis of respiratory viral and fungal coinfections
Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation
Viruses evade the innate immune response by suppressing the production or activity of
cytokines such as type I interferons (IFNs). Here we report the discovery of a mechanism by …
cytokines such as type I interferons (IFNs). Here we report the discovery of a mechanism by …