A comprehensive review on miR-146a molecular mechanisms in a wide spectrum of immune and non-immune inflammatory diseases

SS Mortazavi-Jahromi, M Aslani, A Mirshafiey - Immunology Letters, 2020 - Elsevier
MicroRNAs (miRNAs) are single-strand endogenous and non-coding RNA molecules with a
length of about 22 nucleotides, which regulate genes expression, through modulating the …

Computational approaches and challenges for identification and annotation of non-coding RNAs using RNA-Seq

K Dindhoria, I Monga, AS Thind - Functional & Integrative Genomics, 2022 - Springer
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNASeq applications …

[HTML][HTML] MicroRNA-210 regulates the metabolic and inflammatory status of primary human astrocytes

NW Kieran, R Suresh, MF Dorion, A MacDonald… - Journal of …, 2022 - Springer
Background Astrocytes are the most numerous glial cell type with important roles in
maintaining homeostasis and responding to diseases in the brain. Astrocyte function is …

[HTML][HTML] Expression, regulation, and functions of the galectin-16 gene in human cells and tissues

JD Kaminker, AV Timoshenko - Biomolecules, 2021 - mdpi.com
Galectins comprise a family of soluble β-galactoside-binding proteins, which regulate a
variety of key biological processes including cell growth, differentiation, survival, and death …

[HTML][HTML] Circulating miR-146a as a possible candidate biomarker in the indeterminate phase of Chagas disease

MA Ballinas-Verdugo, RF Jiménez-Ortega… - Biological Research, 2021 - Springer
Background Chagas disease is considered important and presents intense inflammatory
and fibrotic processes induced by the perpetuation of the parasite in the affected tissues and …

[HTML][HTML] miR-195-5p as Regulator of γ-Catenin and Desmosome Junctions in Colorectal Cancer

E Piccinno, V Scalavino, R Armentano… - International Journal of …, 2023 - mdpi.com
Desmosomes play a key role in the regulation of cell adhesion and signaling. Dysregulation
of the desmosome complex is associated with the loss of epithelial cell polarity and …

[HTML][HTML] In silico and in vitro analysis of microRNAs with therapeutic potential in atherosclerosis

M Mahjoubin-Tehran, SH Aghaee-Bakhtiari… - Scientific Reports, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease in which aberrant lipid metabolism plays a
key role. MicroRNAs (miRNAs), micro-coordinators of gene expression, have been recently …

[HTML][HTML] MicroRNAs targeting HIF-2α, VEGFR1 and/or VEGFR2 as potential predictive biomarkers for VEGFR tyrosine kinase and HIF-2α inhibitors in metastatic clear …

L Kinget, E Roussel, A Verbiest, M Albersen… - Cancers, 2021 - mdpi.com
Simple Summary Metastatic clear-cell renal cell carcinoma is characterized by heightened
angiogenesis through increased expression of HIF-2α and VEGFR2. VEGFR tyrosine kinase …

Efficient roles of miR-146a in cellular and molecular mechanisms of neuroinflammatory disorders: an effectual review in neuroimmunology

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - Immunology Letters, 2021 - Elsevier
Known as one of the most sophisticated systems of the human body, the nervous system
consists of neural cells and controls all parts of the body. It is closely related to the immune …

[HTML][HTML] Pharmacological mechanism of NRICM101 for COVID-19 treatments by combined network pharmacology and pharmacodynamics

S Singh, YF Yang - International journal of molecular sciences, 2022 - mdpi.com
Symptom treatments for Coronavirus disease 2019 (COVID-19) infection and Long COVID
are one of the most critical issues of the pandemic era. In light of the lack of standardized …