Magnetic resonance imaging techniques measuring CBF have developed rapidly in the last
decade, resulting in a wide range of available methods. The most successful approaches …

Numerous techniques have been proposed in the last 15 years to measure various
perfusion‐related parameters in the brain. In particular, two approaches have proven …

The mouse is an excellent model for investigations of stroke and neural injury. However,
there is a paucity of long term functional outcome measurements for the mouse. We …

In the investigation of ischemic stroke, conventional structural magnetic resonance (MR)
techniques (eg, T1-weighted imaging, T2-weighted imaging, and proton density-weighted …

We developed a new model of embolic cerebral ischemia in the rat which provides a
reproducible and predictable infarct volume within the territory supplied by the middle …

A reproducible model of thread occlusion of the middle cerebral artery (MCA) was
established in C57 Black/6J mice by matching the diameter of the thread to the weight of the …

We developed a fibrin-rich thrombotic focal cerebral ischemic model with reproducible and
predictable infarct volume in rats. In male Wistar rats (n= 77), a thrombus was induced at the …

The use of hypothermia to mitigate cerebral ischemic injury is not new. From early studies, it
has been clear that cooling is remarkably neuroprotective when applied during global or …

The application of magnetic resonance (MR) imaging in the study of human disease using
small animals has steadily evolved over the past two decades and strongly established the …

Background and Purpose Over the past several years, it has been demonstrated that mild
intraischemic or immediate postischemic hyperthermia worsens ischemic outcome in …