Ingestible electronics for diagnostics and therapy
The gastrointestinal (GI) tract offers the opportunity to detect physiological and
pathophysiological signals from the human body. Ingestible electronics can gain close …
pathophysiological signals from the human body. Ingestible electronics can gain close …
[HTML][HTML] Nrf2 and heme oxygenase-1 involvement in atherosclerosis related oxidative stress
JA Alonso-Piñeiro, A Gonzalez-Rovira… - Antioxidants, 2021 - mdpi.com
Atherosclerosis remains the underlying process responsible for cardiovascular diseases
and the high mortality rates associated. This chronic inflammatory disease progresses with …
and the high mortality rates associated. This chronic inflammatory disease progresses with …
Gas-mediated cancer bioimaging and therapy
Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …
Carbon monoxide signaling: examining its engagement with various molecular targets in the context of binding affinity, concentration, and biologic response
Carbon monoxide (CO) has been firmly established as an endogenous signaling molecule
with a variety of pathophysiological and pharmacological functions, including …
with a variety of pathophysiological and pharmacological functions, including …
Devices for drug delivery in the gastrointestinal tract: A review of systems physically interacting with the mucosa for enhanced delivery
The delivery of macromolecules via the gastrointestinal (GI) tract remains a significant
challenge. A variety of technologies using physical modes of drug delivery have been …
challenge. A variety of technologies using physical modes of drug delivery have been …
A brief history of carbon monoxide and its therapeutic origins
It is estimated that 10% of carbon throughout the cosmos is in the form of carbon monoxide
(CO). Earth's earliest prebiotic atmosphere included the trinity of gasotransmitters CO, nitric …
(CO). Earth's earliest prebiotic atmosphere included the trinity of gasotransmitters CO, nitric …
[HTML][HTML] Carbon monoxide in intensive care medicine—time to start the therapeutic application?!
U Goebel, J Wollborn - Intensive Care Medicine Experimental, 2020 - Springer
Carbon monoxide (CO) is not only known as a toxic gas due to its characteristics as an
odorless molecule and its rapid binding to haem-containing molecules, thus inhibiting the …
odorless molecule and its rapid binding to haem-containing molecules, thus inhibiting the …
[HTML][HTML] Carbon monoxide and a change of heart
LM Chu, S Shaefi, JD Byrne, RWA de Souza… - Redox biology, 2021 - Elsevier
The relationship between carbon monoxide and the heart has been extensively studied in
both clinical and preclinical settings. The Food and Drug Administration (FDA) is keenly …
both clinical and preclinical settings. The Food and Drug Administration (FDA) is keenly …
Where is the clinical breakthrough of heme oxygenase-1/carbon monoxide therapeutics?
Heme oxygenase (HO), the rate-limiting step in the degradation of heme to biliverdin, ferrous
ion, and carbon monoxide (CO), is an ancestral protective enzyme conserved across …
ion, and carbon monoxide (CO), is an ancestral protective enzyme conserved across …
Transdermal carbon monoxide delivery
Overuse injuries or acute trauma in joints often lead to painful tendinopathy, and
pharmacological treatment effects are limited. The site of the disease is hard to reach with …
pharmacological treatment effects are limited. The site of the disease is hard to reach with …