Recent advances in thermo-sensitive hydrogels for drug delivery

Y Yu, Y Cheng, J Tong, L Zhang, Y Wei… - Journal of Materials …, 2021 - pubs.rsc.org
Hydrogels are cross-linked hydrophilic macromolecules that contain a certain amount of
water. Due to their biocompatible, highly tunable and hydrophilic nature, hydrogels have …

Thermo-sensitive nanomaterials: recent advance in synthesis and biomedical applications

P Sánchez-Moreno, J De Vicente, S Nardecchia… - Nanomaterials, 2018 - mdpi.com
Progress in nanotechnology has enabled us to open many new fronts in biomedical
research by exploiting the peculiar properties of materials at the nanoscale. The thermal …

Injectable chitosan-based thermosensitive hydrogel/nanoparticle-loaded system for local delivery of vancomycin in the treatment of osteomyelitis

J Tao, Y Zhang, A Shen, Y Yang, L Diao… - International Journal …, 2020 - Taylor & Francis
Purpose Osteomyelitis, particularly chronic osteomyelitis, remains a major challenge for
orthopedic surgeons. The traditional treatment for osteomyelitis, which involves antibiotics …

Co-administration of amoxicillin-loaded chitosan nanoparticles and inulin: A novel strategy for mitigating antibiotic resistance and preserving microbiota balance in …

B Fayed, J Jagal, R Cagliani, RA Kedia… - International Journal of …, 2023 - Elsevier
Helicobacter pylori (H. pylori) is a causative agent of various gastrointestinal diseases and
eradication mainly relies on antibiotic treatment, with (AMX) being a key component …

Thermosensitive injectable graphene oxide/chitosan-based nanocomposite hydrogels for controlling the in vivo release of bupivacaine hydrochloride

S Eltahir, J Jagal, MA Abdelkareem… - International Journal of …, 2022 - Elsevier
Local anesthetics are commonly used for the management of intraoperative and
postoperative acute and chronic pain caused by small invasive procedures. However, their …

Chitosan with enhanced deprotonation for accelerated thermosensitive gelation with β-glycerophosphate

Y Liu, C Lang, Y Ding, S Sun, G Sun - European Polymer Journal, 2023 - Elsevier
Abstract Chitosan (CS)/β-sodium glycerophosphate (β-GP) gels have low temperature
sensitivity, which limits their biomedical application. The protonation and deprotonation of …

Chitosan as a Functional Carrier for the Local Delivery Anti-Inflammatory Systems Containing Scutellariae baicalensis radix Extract

M Paczkowska-Walendowska, J Cielecka-Piontek - Pharmaceutics, 2022 - mdpi.com
The aim of the study was to establish the influence of chitosan on the preparation of systems
containing Scutellariae baicalensis radix extract and to demonstrate the potential of anti …

Graphene oxide/chitosan injectable composite hydrogel for controlled release of doxorubicin: an approach for enhanced intratumoral delivery

S Eltahir, R Al Homsi, J Jagal, IS Ahmed, M Haider - Nanomaterials, 2022 - mdpi.com
Intratumoral (IT) injection of chemotherapeutics into needle-accessible solid tumors can
directly localize the anticancer drug in the tumor site, thus increasing its local bioavailability …

Optimization and Evaluation of Poly(lactide-co-glycolide) Nanoparticles for Enhanced Cellular Uptake and Efficacy of Paclitaxel in the Treatment of Head and Neck …

M Haider, A Elsherbeny, J Jagal, A Hubatová-Vacková… - Pharmaceutics, 2020 - mdpi.com
The particle size (PS) and encapsulation efficiency (EE%) of drug-loaded nanoparticles
(NPs) may inhibit their cellular uptake and lead to possible leakage of the drug into the …

[HTML][HTML] The protective effects of baicalin for respiratory diseases: an update and future perspectives

S Song, L Ding, G Liu, T Chen, M Zhao, X Li… - Frontiers in …, 2023 - frontiersin.org
Background: Respiratory diseases are common and frequent diseases. Due to the high
pathogenicity and side effects of respiratory diseases, the discovery of new strategies for …