Aflatoxin biosynthesis and genetic regulation: A review

I Caceres, A Al Khoury, R El Khoury, S Lorber… - Toxins, 2020 - mdpi.com
The study of fungal species evolved radically with the development of molecular techniques
and produced new evidence to understand specific fungal mechanisms such as the …

Aspergillus flavus

S Amaike, NP Keller - Annual review of phytopathology, 2011 - annualreviews.org
Aspergillus flavus is saprophytic soil fungus that infects and contaminates preharvest and
postharvest seed crops with the carcinogenic secondary metabolite aflatoxin. The fungus is …

Association of fungal secondary metabolism and sclerotial biology

AM Calvo, JW Cary - Frontiers in Microbiology, 2015 - frontiersin.org
Fungal secondary metabolism and morphological development have been shown to be
intimately associated at the genetic level. Much of the literature has focused on the co …

Distinct Roles for VeA and LaeA in Development and Pathogenesis of Aspergillus flavus

S Amaike, NP Keller - Eukaryotic cell, 2009 - Am Soc Microbiol
Aspergillus flavus, a mycotoxigenic filamentous fungus, colonizes several important
agricultural crops, such as maize and peanuts. Two proteins, VeA and LaeA, known to form …

Two Components of a velvet-Like Complex Control Hyphal Morphogenesis, Conidiophore Development, and Penicillin Biosynthesis in Penicillium chrysogenum

B Hoff, J Kamerewerd, C Sigl, R Mitterbauer… - Eukaryotic …, 2010 - Am Soc Microbiol
Penicillium chrysogenum is the industrial producer of the antibiotic penicillin, whose
biosynthetic regulation is barely understood. Here, we provide a functional analysis of two …

ChLae1 and ChVel1 Regulate T-toxin Production, Virulence, Oxidative Stress Response, and Development of the Maize Pathogen Cochliobolus heterostrophus

D Wu, S Oide, N Zhang, MY Choi, BG Turgeon - PLoS pathogens, 2012 - journals.plos.org
LaeA and VeA coordinate secondary metabolism and differentiation in response to light
signals in Aspergillus spp. Their orthologs, ChLae1 and ChVel1, were identified in the maize …

Secondary Metabolism and Development Is Mediated by LlmF Control of VeA Subcellular Localization in Aspergillus nidulans

JM Palmer, JM Theisen, RM Duran, WS Grayburn… - PLoS …, 2013 - journals.plos.org
Secondary metabolism and development are linked in Aspergillus through the conserved
regulatory velvet complex composed of VeA, VelB, and LaeA. The founding member of the …

The velvet protein Vel1 controls initial plant root colonization and conidia formation for xylem distribution in Verticillium wilt

AM Höfer, R Harting, NF Aßmann, J Gerke… - PLoS …, 2021 - journals.plos.org
The conserved fungal velvet family regulatory proteins link development and secondary
metabolite production. The velvet domain for DNA binding and dimerization is similar to the …

VeA regulates conidiation, gliotoxin production, and protease activity in the opportunistic human pathogen Aspergillus fumigatus

S Dhingra, D Andes, AM Calvo - Eukaryotic cell, 2012 - Am Soc Microbiol
Invasive aspergillosis by Aspergillus fumigatus is a leading cause of infection-related
mortality in immunocompromised patients. In this study, we show that veA, a major …

VeA is associated with the response to oxidative stress in the aflatoxin producer Aspergillus flavus

S Baidya, RM Duran, JM Lohmar… - Eukaryotic …, 2014 - Am Soc Microbiol
Survival of fungal species depends on the ability of these organisms to respond to
environmental stresses. Osmotic stress or high levels of reactive oxygen species (ROS) can …