Crosstalk between inflammatory pathways and neurocircuits in the brain can lead to
behavioural responses, such as avoidance and alarm, that are likely to have provided early …

The innate immune system is dysregulated in depression; however, less is known about the
longitudinal associations of depression and inflammatory biomarkers. We investigated the …

Peripheral blood C-reactive protein (CRP) is a biomarker used clinically to measure
systemic inflammation and is reproducibly increased in a subset of patients with major …

The relationship between living alone, loneliness and social isolation, and how they are
associated with health remain contentious. We sought to explore typologies based on …

Findings from numerous laboratories and across neuroimaging modalities have consistently
shown that exogenous administration of cytokines or inflammatory stimuli that induce …

Introduction Population-based studies have associated inflammation, particularly higher C-
reactive protein (CRP), with depressive severity, but clinical trials in major depressive …

Previous research indicates there may be an association between inflammation and
depression in older adults but results are inconsistent. Therefore, the aim of this review was …

Introduction: Previous investigations have demonstrated that major depression is associated
with particular patterns of cytokine signalling. The primary aim of this study was to examine …

Vitamins are dietary components which are necessary for life. They play a major role in
health and their deficiency may be linked to symptoms of psychiatric disorders. B vitamins …

Major depressive disorder (MDD) is characterized by psychological and physiological
manifestations contributing to the disease severity and outcome. In recent years, several …