[HTML][HTML] Treatment resistance in psychiatry: state of the art and new directions
OD Howes, ME Thase, T Pillinger - Molecular psychiatry, 2022 - nature.com
Abstract Treatment resistance affects 20–60% of patients with psychiatric disorders; and is
associated with increased healthcare burden and costs up to ten-fold higher relative to …
associated with increased healthcare burden and costs up to ten-fold higher relative to …
A dopamine hypothesis of autism spectrum disorder
D Pavăl - Developmental neuroscience, 2017 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have …
characterized by social deficits and stereotyped behaviors. While several theories have …
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan… - Nature …, 2013 - nature.com
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic
variation is unique to individual disorders or shared across disorders is unclear. To examine …
variation is unique to individual disorders or shared across disorders is unclear. To examine …
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
Cross-Disorder Group of the Psychiatric Genomics … - The Lancet, 2013 - Elsevier
BACKGROUND: Findings from family and twin studies suggest that genetic contributions to
psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to …
psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to …
A small number of abnormal brain connections predicts adult autism spectrum disorder
Although autism spectrum disorder (ASD) is a serious lifelong condition, its underlying
neural mechanism remains unclear. Recently, neuroimaging-based classifiers for ASD and …
neural mechanism remains unclear. Recently, neuroimaging-based classifiers for ASD and …
Automatic imitation: A meta-analysis.
Automatic imitation is the finding that movement execution is facilitated by compatible and
impeded by incompatible observed movements. In the past 15 years, automatic imitation has …
impeded by incompatible observed movements. In the past 15 years, automatic imitation has …
Varieties of Self Disorder: A Bio-Pheno-Social Model of Schizophrenia
L Sass, JP Borda, L Madeira, E Pienkos… - Schizophrenia …, 2018 - academic.oup.com
The self-disorder model offers a unifying way of conceptualizing schizophrenia's highly
diverse symptoms (positive, negative, disorganized), of capturing their distinctive …
diverse symptoms (positive, negative, disorganized), of capturing their distinctive …
Mice with Shank3 mutations associated with ASD and schizophrenia display both shared and distinct defects
Genetic studies have revealed significant overlaps of risk genes among psychiatric
disorders. However, it is not clear how different mutations of the same gene contribute to …
disorders. However, it is not clear how different mutations of the same gene contribute to …
Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other …
JL Allen, G Oberdorster, K Morris-Schaffer, C Wong… - Neurotoxicology, 2017 - Elsevier
Accumulating evidence from both human and animal studies show that brain is a target of air
pollution. Multiple epidemiological studies have now linked components of air pollution to …
pollution. Multiple epidemiological studies have now linked components of air pollution to …
Activation of the maternal immune system during pregnancy alters behavioral development of rhesus monkey offspring
Background Maternal infection during pregnancy is associated with an increased risk of
schizophrenia and autism in the offspring. Supporting this correlation, experimentally …
schizophrenia and autism in the offspring. Supporting this correlation, experimentally …