[HTML][HTML] Treatment resistance in psychiatry: state of the art and new directions

OD Howes, ME Thase, T Pillinger - Molecular psychiatry, 2022 - nature.com
Abstract Treatment resistance affects 20–60% of patients with psychiatric disorders; and is
associated with increased healthcare burden and costs up to ten-fold higher relative to …

A dopamine hypothesis of autism spectrum disorder

D Pavăl - Developmental neuroscience, 2017 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have …

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan… - Nature …, 2013 - nature.com
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic
variation is unique to individual disorders or shared across disorders is unclear. To examine …

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Cross-Disorder Group of the Psychiatric Genomics … - The Lancet, 2013 - Elsevier
BACKGROUND: Findings from family and twin studies suggest that genetic contributions to
psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to …

A small number of abnormal brain connections predicts adult autism spectrum disorder

N Yahata, J Morimoto, R Hashimoto, G Lisi… - Nature …, 2016 - nature.com
Although autism spectrum disorder (ASD) is a serious lifelong condition, its underlying
neural mechanism remains unclear. Recently, neuroimaging-based classifiers for ASD and …

Automatic imitation: A meta-analysis.

E Cracco, L Bardi, C Desmet, O Genschow… - Psychological …, 2018 - psycnet.apa.org
Automatic imitation is the finding that movement execution is facilitated by compatible and
impeded by incompatible observed movements. In the past 15 years, automatic imitation has …

Varieties of Self Disorder: A Bio-Pheno-Social Model of Schizophrenia

L Sass, JP Borda, L Madeira, E Pienkos… - Schizophrenia …, 2018 - academic.oup.com
The self-disorder model offers a unifying way of conceptualizing schizophrenia's highly
diverse symptoms (positive, negative, disorganized), of capturing their distinctive …

Mice with Shank3 mutations associated with ASD and schizophrenia display both shared and distinct defects

Y Zhou, T Kaiser, P Monteiro, X Zhang… - Neuron, 2016 - cell.com
Genetic studies have revealed significant overlaps of risk genes among psychiatric
disorders. However, it is not clear how different mutations of the same gene contribute to …

Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other …

JL Allen, G Oberdorster, K Morris-Schaffer, C Wong… - Neurotoxicology, 2017 - Elsevier
Accumulating evidence from both human and animal studies show that brain is a target of air
pollution. Multiple epidemiological studies have now linked components of air pollution to …

Activation of the maternal immune system during pregnancy alters behavioral development of rhesus monkey offspring

MD Bauman, AM Iosif, SEP Smith, C Bregere… - Biological …, 2014 - Elsevier
Background Maternal infection during pregnancy is associated with an increased risk of
schizophrenia and autism in the offspring. Supporting this correlation, experimentally …