Coagulation abnormalities and thrombosis in patients infected with SARS-CoV-2 and other pandemic viruses
N Mackman, S Antoniak, AS Wolberg… - … , and vascular biology, 2020 - Am Heart Assoc
The world is amid a pandemic caused by severe acute respiratory syndrome-coronavirus 2.
Severe acute respiratory syndrome-coronavirus causes serious respiratory tract infections …
Severe acute respiratory syndrome-coronavirus causes serious respiratory tract infections …
Overview: systemic inflammatory response derived from lung injury caused by SARS-CoV-2 infection explains severe outcomes in COVID-19
Most SARS-CoV2 infections will not develop into severe COVID-19. However, in some
patients, lung infection leads to the activation of alveolar macrophages and lung epithelial …
patients, lung infection leads to the activation of alveolar macrophages and lung epithelial …
Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration
CP Sodhi, C Wohlford-Lenane… - … of Physiology-Lung …, 2018 - journals.physiology.org
Angiotensin-converting enzyme 2 (ACE2) is a terminal carboxypeptidase with important
functions in the renin-angiotensin system and plays a critical role in inflammatory lung …
functions in the renin-angiotensin system and plays a critical role in inflammatory lung …
SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy
Background SARS-CoV-2 enters cells by binding of its spike protein to angiotensin-
converting enzyme 2 (ACE2). Angiotensin-converting enzyme inhibitors (ACEIs) or …
converting enzyme 2 (ACE2). Angiotensin-converting enzyme inhibitors (ACEIs) or …
Pulmonary angiotensin-converting enzyme 2 (ACE2) and inflammatory lung disease
H Jia - Shock, 2016 - journals.lww.com
In response to infectious and, in some instances, noninfectious insults, the affected
tissues/cells of the host undergo inflammation. However, uncontrolled inflammation could be …
tissues/cells of the host undergo inflammation. However, uncontrolled inflammation could be …
[HTML][HTML] The role of saliva in tick feeding
When attempting to feed on their hosts, ticks face the problem of host hemostasis (the
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …
Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing
Prolonged unaccustomed exercise involving muscle lengthening (eccentric) actions can
result in ultrastructural muscle disruption, impaired excitation–contraction coupling …
result in ultrastructural muscle disruption, impaired excitation–contraction coupling …
Immunological mechanisms in the pathogenesis of diabetic retinopathy
AP Adamis, AJ Berman - Seminars in immunopathology, 2008 - Springer
There is an accumulating body of evidence that immunological mechanisms play a
prominent role in the pathogenesis of diabetic retinopathy (DR), which is characterized by …
prominent role in the pathogenesis of diabetic retinopathy (DR), which is characterized by …
Molecular targets of antihypertensive peptides: understanding the mechanisms of action based on the pathophysiology of hypertension
K Majumder, J Wu - International journal of molecular sciences, 2014 - mdpi.com
There is growing interest in using functional foods or nutraceuticals for the prevention and
treatment of hypertension or high blood pressure. Although numerous preventive and …
treatment of hypertension or high blood pressure. Although numerous preventive and …
The renin–angiotensin system biomolecular cascade: a 2022 update of newer insights and concepts
CM Ferrario, L Groban, H Wang, X Sun… - Kidney international …, 2022 - Elsevier
A large body of evidence implicates the renin–angiotensin system in the pathogenesis of
cardiovascular disease. However, not everyone understands that the magnitude of the risk …
cardiovascular disease. However, not everyone understands that the magnitude of the risk …