[Retracted] Biomedical Implications of Heavy Metals Induced Imbalances in Redox Systems

B Sharma, S Singh, NJ Siddiqi - BioMed research international, 2014 - Wiley Online Library
Several workers have extensively worked out the metal induced toxicity and have reported
the toxic and carcinogenic effects of metals in human and animals. It is well known that these …

[HTML][HTML] Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

AC Famurewa, K Renu, MA Eladl… - Biomedicine & …, 2022 - Elsevier
Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …

Arsenic-induced oxidative stress and its reversibility

SJS Flora - Free Radical Biology and Medicine, 2011 - Elsevier
This review summarizes the literature describing the molecular mechanisms of arsenic-
induced oxidative stress, its relevant biomarkers, and its relation to various diseases …

Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Heavy metal induced oxidative stress & its possible reversal by chelation therapy

SJS Flora, M Mittal, A Mehta - Indian Journal of Medical Research, 2008 - journals.lww.com
Exposure to heavy metals is a common phenomenon due to their environmental
pervasiveness. Metal intoxication particularly neurotoxicity, genotoxicity, or carcinogenicity is …

Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure

SJS Flora - Oxidative medicine and cellular longevity, 2009 - Wiley Online Library
Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid.
Beneficial renal effects of some medications, such as chelation therapy depend at least …

Environmental toxicity, oxidative stress and apoptosis: menage a trois

R Franco, R Sánchez-Olea, EM Reyes-Reyes… - … /Genetic Toxicology and …, 2009 - Elsevier
Apoptosis is an evolutionary conserved homeostatic process involved in distinct
physiological processes including organ and tissue morphogenesis, development and …

The central role of glutathione in the pathophysiology of human diseases

R Franco, OJ Schoneveld, A Pappa… - Archives of physiology …, 2007 - Taylor & Francis
Reduced glutathione (L-γ-glutamyl-L-cysteinyl-glycine, GSH) is the prevalent low-molecular-
weight thiol in mammalian cells. It is formed in a two-step enzymatic process including, first …

[HTML][HTML] The promising future of nano-antioxidant therapy against environmental pollutants induced-toxicities

A Eftekhari, SM Dizaj, L Chodari, S Sunar… - Biomedicine & …, 2018 - Elsevier
Developmental toxicity caused by exposure to a mixture of environmental pollutants has
become a major health concern. Human-made chemicals, including xenoestrogens …

An appraisal on molecular and biochemical signalling cascades during arsenic-induced hepatotoxicity

K Renu, A Saravanan, A Elangovan, S Ramesh… - Life sciences, 2020 - Elsevier
Arsenic is a ubiquitous metalloid compound commonly found in the environment, and it is
usually found in combination with sulphur and metals. Arsenic is considered as a …