The intracellular calcium concentration ([Ca 2+]) has important roles in the triggering of
neurotransmitter release and the regulation of short-term plasticity (STP). Transmitter …

The neuronal and synaptic organisation of the cerebral cortex appears exceedingly
complex, and the definition of a basic cortical circuit in terms of defined classes of cells and …

CALCIUM entry through presynaptic calcium channels controls the release of
neurotransmitter1. It is not known whether the putative calcium sensor that triggers this rapid …

Atomic force microscopy (AFM) is part of a range of emerging microscopic methods for
biologists which offer the magnification range of both the light and electron microscope, but …

This book provides the reader with an account of some of the experimental evidence on
which our present knowledge is based. The third edition of this highly successful book has …

Synapses are not static; their performance is modified adaptively in response to activity.
Presynaptic mechanisms that affect the probability of transmitter release or the amount of …

Active zones are highly specialized sites for release of neurotransmitter from presynaptic
nerve terminals. The architecture of the active zone is exquisitely designed to facilitate the …

Simple approximations to some limiting cases of Ca++ signalling provide insight into the
complex problems of buffered diffusion and of Ca++ homeostasis in the presence of buffers …

The primary function of the presynaptic nerve terminal is to release transmitter quanta and
thus activate the postsynaptic target cell. In almost every step leading to the release of …

Although N-and P-type Ca2+ channels predominant in fast-secreting systems, Lc-type Ca2+
channels (C-class) can play a similar role in certain secretory cells and synapses. For …