Responsive fluorescent probes for cellular microenvironment and redox small biomolecules

L Zhang, L Zhang, X Zhang, Y Zhao, S Fang… - TrAC Trends in …, 2023 - Elsevier
The living system is critically depended on the inner microenvironment and redox small
biomolecules to maintain the normal physiological processes. Consequently, tracing and …

Activatable Probes for Ratiometric Imaging of Endogenous Biomarkers In Vivo

Q Fu, X Yang, M Wang, K Zhu, Y Wang, J Song - ACS nano, 2024 - ACS Publications
Dynamic variations in the concentration and abnormal distribution of endogenous
biomarkers are strongly associated with multiple physiological and pathological states …

Self-assembled nano-photosensitizer for targeted, activatable, and biosafe cancer phototheranostics

K Cheng, J Qi, J Zhang, H Li, X Ren, W Wei, L Meng… - Biomaterials, 2022 - Elsevier
Cancer treatment currently still faces crucial challenges in therapeutic effectiveness,
precision, and complexity. Photodynamic therapy (PDT) as a non-invasive tactic has earned …

A Self‐Sustaining Near‐Infrared Afterglow Chemiluminophore for High‐Contrast Activatable Imaging

J Zhu, W Chen, L Yang, Y Zhang… - Angewandte Chemie …, 2024 - Wiley Online Library
Afterglow imaging holds great promise for ultrasensitive bioimaging due to its elimination of
autofluorescence. Self‐sustaining afterglow molecules (SAMs), which enable all‐in‐one …

Carbon Monoxide: A Second Biomarker to Couple with Viscosity for the Construction of “Dual-Locked” Near-Infrared Fluorescent Probes for Accurately Diagnosing …

S Han, Y Zeng, Y Li, H Li, L Yang, X Ren… - Analytical …, 2023 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD) can progress to cirrhosis and liver cancer if left
untreated. Therefore, it is of great importance to develop useful tools for the noninvasive and …

Nanozyme Sensor Array Based on Porphyrin-Modified CoMoO4 to Detect and Distinguish Biologically Important Thiols

P Hao, Y Liu, L Wang, X Zhu, Q Liu - ACS Applied Nano Materials, 2023 - ACS Publications
In order to establish a rapid, accurate, and simple method for monitoring and analyzing the
biological physiological state, we constructed a colorimetric sensor array based on the …

Recent progress in the rational design of biothiol-responsive fluorescent probes

W Xie, J Jiang, D Shu, Y Zhang, S Yang, K Zhang - Molecules, 2023 - mdpi.com
Biothiols such as cysteine, homocysteine, and glutathione play significant roles in important
biological activities, and their abnormal concentrations have been found to be closely …

New insight into the application of fluorescence platforms in tumor diagnosis: From chemical basis to clinical application

Y Li, Q Chen, X Pan, W Lu… - Medicinal Research …, 2023 - Wiley Online Library
Early and rapid diagnosis of tumors is essential for clinical treatment or management. In
contrast to conventional means, bioimaging has the potential to accurately locate and …

Methylene blue-based near-infrared activatable probes for bioimaging

S Li, P Wang, K Yang, Y Liu, D Cheng, L He - Dyes and Pigments, 2023 - Elsevier
A near-infrared methylene blue-based fluorogenic probe with an on/off activation ability has
emerged as an important means to detect and monitor biological analytes and to understand …

Glutathione‐triggered prodrugs: Design strategies, potential applications, and perspectives

J Zhao, X Li, T Ma, B Chang, B Zhang… - Medicinal Research …, 2024 - Wiley Online Library
The burgeoning prodrug strategy offers a promising avenue toward improving the efficacy
and specificity of cytotoxic drugs. Elevated intracellular levels of glutathione (GSH) have …