Importance Antimicrobial resistance continues to spread rapidly at a global scale. Little
evidence exists on the association of antimicrobial stewardship programs (ASPs) with the …

In accordance with the recommendations of, amongst others, the Surviving Sepsis
Campaign and the recently published European treatment guidelines for hospital-acquired …

Background Antimicrobial de-escalation (ADE) is a strategy of antimicrobial stewardship,
aiming at preventing the emergence of antimicrobial resistance (AMR) by decreasing the …

With the increase of antibiotic resistance currently available at an alarming rate, new
improved films of Chitosan (CS) have been achieved with different levels of Tigecycline …

Purpose The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of
empirical treatment is performed in the intensive care unit (ICU) and to estimate the effect of …

Objective Information from critically ill coronavirus disease 2019 (COVID-19) patients is
limited and in many cases coming from health systems approaches different from the …

Introduction: Despite advances in modern medicine, severe community-acquired
pneumonia (CAP) continues to be a potentially deadly disease. Mortality rate reaches up to …

Abstract Background Antimicrobial stewardship programs (ASPs) using audit and feedback
in the intensive care unit (ICU) setting can reduce harms related to inappropriate antibiotic …

Due to multidrug resistance, microbial infections have become significant on a global level.
As infections caused by several resistant bacteria and fungi severely harm mankind …

The rise of infections caused by multi-resistant gram-negative bacilli (MR-GNB), which
includes carbapenems, represents one of the major current challenges worldwide. These …