Oxytocin: the great facilitator of life

HJ Lee, AH Macbeth, JH Pagani, WS Young 3rd - Progress in neurobiology, 2009 - Elsevier
Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …

Developmental perspectives on oxytocin and vasopressin

EAD Hammock - Neuropsychopharmacology, 2015 - nature.com
The related neuropeptides oxytocin and vasopressin are involved in species-typical
behavior, including social recognition behavior, maternal behavior, social bonding …

A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene

F Schaller, F Watrin, R Sturny… - Human molecular …, 2010 - academic.oup.com
The onset of feeding at birth is a vital step for the adaptation of the neonate to extra uterine
life. Prader–Willi syndrome (PWS) is a complex neurogenetic disorder caused by the …

Sex differences and developmental effects of oxytocin on aggression and social behavior in prairie voles (Microtus ochrogaster)

KL Bales, CS Carter - Hormones and behavior, 2003 - Elsevier
Various hormones, including sex steroids and neuropeptides, have been implicated in
aggression. In this study we examined (1) sex differences in intrasexual aggression in naïve …

Mechanisms underlying epigenetic effects of early social experience: the role of neuropeptides and steroids

BS Cushing, KM Kramer - Neuroscience & Biobehavioral Reviews, 2005 - Elsevier
In mammals the neonatal period is a time of significant social interaction. This is true even in
solitary species as females spend a significant amount of time nursing and caring for their …

Oxytocin has dose-dependent developmental effects on pair-bonding and alloparental care in female prairie voles

KL Bales, JA van Westerhuyzen, AD Lewis-Reese… - Hormones and …, 2007 - Elsevier
The present study examines the developmental consequences of neonatal exposure to
oxytocin on adult social behaviors in female prairie voles (Microtus ochrogaster). Female …

Neonatal oxytocin manipulations have long-lasting, sexually dimorphic effects on vasopressin receptors

KL Bales, PM Plotsky, LJ Young, MM Lim, N Grotte… - Neuroscience, 2007 - Elsevier
Developmental exposure to oxytocin (OT) or oxytocin antagonists (OTAs) has been shown to
cause long-lasting and often sexually dimorphic effects on social behaviors in prairie voles …

Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in …

DS Carson, GE Hunt, AJ Guastella, L Barber… - Addiction …, 2010 - Wiley Online Library
Recent preclinical evidence indicates that the neuropeptide oxytocin may have potential in
the treatment of drug dependence and drug withdrawal. Oxytocin reduces …

Neonatal oxytocin treatment ameliorates autistic-like behaviors and oxytocin deficiency in valproic acid-induced rat model of autism

YC Dai, HF Zhang, M Schön, TM Böckers… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) is characterized by impaired social communication and
repetitive/stereotyped behaviors. The neuropeptide oxytocin (OXT) plays a critical role in …

Behavioral and epigenetic consequences of oxytocin treatment at birth

WM Kenkel, AM Perkeybile, JR Yee… - Science …, 2019 - science.org
Oxytocin is used in approximately half of all births in the United States during labor induction
and/or augmentation. However, the effects of maternal oxytocin administration on offspring …