An overview of mammographic density and its association with breast cancer
SS Nazari, P Mukherjee - Breast cancer, 2018 - Springer
In 2017, breast cancer became the most commonly diagnosed cancer among women in the
US. After lung cancer, breast cancer is the leading cause of cancer-related mortality in …
US. After lung cancer, breast cancer is the leading cause of cancer-related mortality in …
The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems
The epithelial-mesenchymal transition (EMT) is intrinsically linked to alterations of the
intracellular cytoskeleton and the extracellular matrix. After EMT, cells acquire an elongated …
intracellular cytoskeleton and the extracellular matrix. After EMT, cells acquire an elongated …
Breast cancer models: Engineering the tumor microenvironment
The mechanisms behind cancer initiation and progression are not clear. Therefore,
development of clinically relevant models to study cancer biology and drug response in …
development of clinically relevant models to study cancer biology and drug response in …
Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis
Cell migration regulates diverse (patho) physiological processes, including cancer
metastasis. According to the Osmotic Engine Model, polarization of NHE1 at the leading …
metastasis. According to the Osmotic Engine Model, polarization of NHE1 at the leading …
3D In Vitro Models for Investigating the Role of Stiffness in Cancer Invasion
A Micalet, E Moeendarbary… - ACS Biomaterials Science …, 2021 - ACS Publications
Background: Tumorigenesis is attributed to the interactions of cancer cells with the tumor
microenvironment through both biochemical cues and physical stimuli. Increased matrix …
microenvironment through both biochemical cues and physical stimuli. Increased matrix …
Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma
A Palamidessi, C Malinverno, E Frittoli, S Corallino… - Nature materials, 2019 - nature.com
During wound repair, branching morphogenesis and carcinoma dissemination, cellular
rearrangements are fostered by a solid-to-liquid transition, known as unjamming. The …
rearrangements are fostered by a solid-to-liquid transition, known as unjamming. The …
Material approaches to active tissue mechanics
Communities of epithelial cells communicate through intercellular interactions, allowing
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …
Rheological properties of coordinated physical gelation and chemical crosslinking in gelatin methacryloyl (GelMA) hydrogels
AT Young, OC White, MA Daniele - Macromolecular bioscience, 2020 - Wiley Online Library
Synthetically modified proteins, such as gelatin methacryloyl (GelMA), are growing in
popularity for bioprinting and biofabrication. GelMA is a photocurable macromer that can …
popularity for bioprinting and biofabrication. GelMA is a photocurable macromer that can …
Cell–extracellular matrix dynamics
AD Doyle, SS Nazari, KM Yamada - Physical biology, 2022 - iopscience.iop.org
The sites of interaction between a cell and its surrounding microenvironment serve as
dynamic signaling hubs that regulate cellular adaptations during developmental processes …
dynamic signaling hubs that regulate cellular adaptations during developmental processes …
Embedded bioprinting of breast tumor cells and organoids using low‐concentration collagen‐based bioinks
Bioinks for 3D bioprinting of tumor models should not only meet printability requirements but
also accurately maintain and support phenotypes of tumor surrounding cells to recapitulate …
also accurately maintain and support phenotypes of tumor surrounding cells to recapitulate …